The loop2 insertion of type IX myosin acts as an electrostatic actin tether that permits processive movement.

Although class IX myosins are single-headed, they demonstrate characteristics of processive movement along actin filaments. Double-headed myosins that move processively along actin filaments achieve this by successive binding of the two heads in a hand-over-hand mechanism. This mechanism, obviously,...

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Bibliographic Details
Main Authors: Kerstin Elfrink, Wanqin Liao, Uwe Pieper, Stefanie J Oeding, Martin Bähler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3887004?pdf=render

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