Red cell distribution width and early mortality in elderly patients with severe sepsis and septic shock
Objective To investigate the association of red cell distribution width (RDW) with 30-day mortality in elderly patients with severe sepsis and septic shock. Methods Patients were recruited from a single tertiary emergency department. Patients with age over 65 years were selected. The main outcome wa...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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The Korean Society of Emergency Medicine
2015-09-01
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| Series: | Clinical and Experimental Emergency Medicine |
| Subjects: | |
| Online Access: | http://www.ceemjournal.org/upload/pdf/ceem-15-037.pdf |
| _version_ | 1797897216799539200 |
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| author | Sejin Kim Kyoungmi Lee Inbyung Kim Siyoung Jung Moon-Jung Kim |
| author_facet | Sejin Kim Kyoungmi Lee Inbyung Kim Siyoung Jung Moon-Jung Kim |
| author_sort | Sejin Kim |
| collection | DOAJ |
| description | Objective To investigate the association of red cell distribution width (RDW) with 30-day mortality in elderly patients with severe sepsis and septic shock. Methods Patients were recruited from a single tertiary emergency department. Patients with age over 65 years were selected. The main outcome was 30-day mortality. Potential confounders as Acute Physiologic and Chronic Health Evaluation (APACHE) II score and Sequential Organ Failure Assessment (SOFA) score along with initial vital signs were collected. Multivariate Cox proportional hazards analysis was performed to identify independent predictors of 30-day mortality. The discriminative ability of RDW for 30-day mortality was evaluated using receiver operating characteristic curve analysis. Results Overall, 458 patients were included. Univariate analysis showed that patients’ survival was significantly associated with sites of infection, comorbidities, and severity scores. In the multivariate Cox proportional hazard model, the RDW was an independent predictor of 30-day mortality (hazards ratio, 1.10; 95% confidence interval, 1.04 to 1.17; P<0.001). Conclusion In this study, initial RDW values were significantly associated with 30-day mortality in older patients hospitalized with severe sepsis and septic shock. |
| first_indexed | 2024-04-10T07:54:04Z |
| format | Article |
| id | doaj.art-44049aae8aba4e9a87479a47193a9b07 |
| institution | Directory Open Access Journal |
| issn | 2383-4625 |
| language | English |
| last_indexed | 2024-04-10T07:54:04Z |
| publishDate | 2015-09-01 |
| publisher | The Korean Society of Emergency Medicine |
| record_format | Article |
| series | Clinical and Experimental Emergency Medicine |
| spelling | doaj.art-44049aae8aba4e9a87479a47193a9b072023-02-23T05:31:07ZengThe Korean Society of Emergency MedicineClinical and Experimental Emergency Medicine2383-46252015-09-012315516110.15441/ceem.15.03750Red cell distribution width and early mortality in elderly patients with severe sepsis and septic shockSejin Kim0Kyoungmi Lee1Inbyung Kim2Siyoung Jung3Moon-Jung Kim4 Department of Emergency Medicine, Myongji Hospital, Goyang, Korea Department of Emergency Medicine, Myongji Hospital, Goyang, Korea Department of Emergency Medicine, Myongji Hospital, Goyang, Korea Department of Emergency Medicine, Myongji Hospital, Goyang, Korea Department of Laboratory Medicine, Myongji Hospital, Goyang, KoreaObjective To investigate the association of red cell distribution width (RDW) with 30-day mortality in elderly patients with severe sepsis and septic shock. Methods Patients were recruited from a single tertiary emergency department. Patients with age over 65 years were selected. The main outcome was 30-day mortality. Potential confounders as Acute Physiologic and Chronic Health Evaluation (APACHE) II score and Sequential Organ Failure Assessment (SOFA) score along with initial vital signs were collected. Multivariate Cox proportional hazards analysis was performed to identify independent predictors of 30-day mortality. The discriminative ability of RDW for 30-day mortality was evaluated using receiver operating characteristic curve analysis. Results Overall, 458 patients were included. Univariate analysis showed that patients’ survival was significantly associated with sites of infection, comorbidities, and severity scores. In the multivariate Cox proportional hazard model, the RDW was an independent predictor of 30-day mortality (hazards ratio, 1.10; 95% confidence interval, 1.04 to 1.17; P<0.001). Conclusion In this study, initial RDW values were significantly associated with 30-day mortality in older patients hospitalized with severe sepsis and septic shock.http://www.ceemjournal.org/upload/pdf/ceem-15-037.pdfsepsismortalityerythrocyte indices |
| spellingShingle | Sejin Kim Kyoungmi Lee Inbyung Kim Siyoung Jung Moon-Jung Kim Red cell distribution width and early mortality in elderly patients with severe sepsis and septic shock Clinical and Experimental Emergency Medicine sepsis mortality erythrocyte indices |
| title | Red cell distribution width and early mortality in elderly patients with severe sepsis and septic shock |
| title_full | Red cell distribution width and early mortality in elderly patients with severe sepsis and septic shock |
| title_fullStr | Red cell distribution width and early mortality in elderly patients with severe sepsis and septic shock |
| title_full_unstemmed | Red cell distribution width and early mortality in elderly patients with severe sepsis and septic shock |
| title_short | Red cell distribution width and early mortality in elderly patients with severe sepsis and septic shock |
| title_sort | red cell distribution width and early mortality in elderly patients with severe sepsis and septic shock |
| topic | sepsis mortality erythrocyte indices |
| url | http://www.ceemjournal.org/upload/pdf/ceem-15-037.pdf |
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