Adrenocortical Carcinoma with a Renal Vein Thrombus Extending to the Inferior Vena Cava Successfully Resected with the Left Kidney and Distal Pancreatectomy: A Case Report
Introduction: Adrenocortical carcinoma (ACC) is an extremely rare and aggressive tumor, and its clinical characteristics are poorly defined because of its rarity. Case Presentation: We report a 64-year-old man who presented with upper abdominal pain and weight loss. Computed tomography revealed a 15...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2024-02-01
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| Series: | Case Reports in Oncology |
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| Online Access: | https://beta.karger.com/Article/FullText/535367 |
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| author | Takashi Miyata Yuta Sannomiya Taigo Nagayama Ryosuke Kin Hisashi Nishiki Akifumi Hashimoto Daisuke Kaida Hideto Fujita Nobuhiko Ueda Hiroyuki Takamura |
| author_facet | Takashi Miyata Yuta Sannomiya Taigo Nagayama Ryosuke Kin Hisashi Nishiki Akifumi Hashimoto Daisuke Kaida Hideto Fujita Nobuhiko Ueda Hiroyuki Takamura |
| author_sort | Takashi Miyata |
| collection | DOAJ |
| description | Introduction: Adrenocortical carcinoma (ACC) is an extremely rare and aggressive tumor, and its clinical characteristics are poorly defined because of its rarity. Case Presentation: We report a 64-year-old man who presented with upper abdominal pain and weight loss. Computed tomography revealed a 15 cm left adrenal tumor compressing the pancreas ventrally and a tumor thrombus in the inferior vena cava (IVC) originating from the left renal vein. Positron emission tomography-computed tomography revealed 18F-fluorodeoxyglucose uptake only in the tumor and tumor thrombus, and radical surgery was planned. Intraoperatively, the tumor was visible on the posterior stomach wall, and the tumor adhered to the pancreas and left kidney. We excised the tumor with part of the pancreas and the left kidney and excised the thrombus from the IVC after clamping. The final diagnosis was ACC, tumor-node-metastasis grade T3N1M0, stage III. The patient received chemotherapy and radiotherapy postoperatively; however, two liver metastases appeared 6 months after surgery. Chemotherapy was continued, and no exacerbation of the liver metastases was observed. Posterior segment resection of the liver was performed 16 months after the initial surgery. Conclusion: This report of a rare case of ACC involving the pancreas with tumor thrombus extension to the IVC stresses that this combination of conditions does not preclude radical surgery. However, more data are needed regarding chemotherapy and radiotherapy, as well as relapse treatment, and further research on ACC is essential for a favorable prognosis. |
| first_indexed | 2024-03-07T19:38:26Z |
| format | Article |
| id | doaj.art-44072ea123a6446dbdaa748678bad7b3 |
| institution | Directory Open Access Journal |
| issn | 1662-6575 |
| language | English |
| last_indexed | 2024-04-24T21:39:15Z |
| publishDate | 2024-02-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Oncology |
| spelling | doaj.art-44072ea123a6446dbdaa748678bad7b32024-03-21T08:27:29ZengKarger PublishersCase Reports in Oncology1662-65752024-02-0117137738510.1159/000535367535367Adrenocortical Carcinoma with a Renal Vein Thrombus Extending to the Inferior Vena Cava Successfully Resected with the Left Kidney and Distal Pancreatectomy: A Case ReportTakashi Miyata0Yuta Sannomiya1Taigo Nagayama2Ryosuke Kin3Hisashi Nishiki4Akifumi Hashimoto5Daisuke Kaida6Hideto Fujita7Nobuhiko Ueda8Hiroyuki Takamura9Department of General and Digestive Surgery, Kanazawa Medical University Hospital, Ishikawa, JapanDepartment of General and Digestive Surgery, Kanazawa Medical University Hospital, Ishikawa, JapanDepartment of General and Digestive Surgery, Kanazawa Medical University Hospital, Ishikawa, JapanDepartment of General and Digestive Surgery, Kanazawa Medical University Hospital, Ishikawa, JapanDepartment of General and Digestive Surgery, Kanazawa Medical University Hospital, Ishikawa, JapanDepartment of General and Digestive Surgery, Kanazawa Medical University Hospital, Ishikawa, JapanDepartment of General and Digestive Surgery, Kanazawa Medical University Hospital, Ishikawa, JapanDepartment of General and Digestive Surgery, Kanazawa Medical University Hospital, Ishikawa, JapanDepartment of General and Digestive Surgery, Kanazawa Medical University Hospital, Ishikawa, JapanDepartment of General and Digestive Surgery, Kanazawa Medical University Hospital, Ishikawa, JapanIntroduction: Adrenocortical carcinoma (ACC) is an extremely rare and aggressive tumor, and its clinical characteristics are poorly defined because of its rarity. Case Presentation: We report a 64-year-old man who presented with upper abdominal pain and weight loss. Computed tomography revealed a 15 cm left adrenal tumor compressing the pancreas ventrally and a tumor thrombus in the inferior vena cava (IVC) originating from the left renal vein. Positron emission tomography-computed tomography revealed 18F-fluorodeoxyglucose uptake only in the tumor and tumor thrombus, and radical surgery was planned. Intraoperatively, the tumor was visible on the posterior stomach wall, and the tumor adhered to the pancreas and left kidney. We excised the tumor with part of the pancreas and the left kidney and excised the thrombus from the IVC after clamping. The final diagnosis was ACC, tumor-node-metastasis grade T3N1M0, stage III. The patient received chemotherapy and radiotherapy postoperatively; however, two liver metastases appeared 6 months after surgery. Chemotherapy was continued, and no exacerbation of the liver metastases was observed. Posterior segment resection of the liver was performed 16 months after the initial surgery. Conclusion: This report of a rare case of ACC involving the pancreas with tumor thrombus extension to the IVC stresses that this combination of conditions does not preclude radical surgery. However, more data are needed regarding chemotherapy and radiotherapy, as well as relapse treatment, and further research on ACC is essential for a favorable prognosis.https://beta.karger.com/Article/FullText/535367adrenocortical carcinomatumor thrombusinferior vena cavaadjuvant therapyradiotherapycase report |
| spellingShingle | Takashi Miyata Yuta Sannomiya Taigo Nagayama Ryosuke Kin Hisashi Nishiki Akifumi Hashimoto Daisuke Kaida Hideto Fujita Nobuhiko Ueda Hiroyuki Takamura Adrenocortical Carcinoma with a Renal Vein Thrombus Extending to the Inferior Vena Cava Successfully Resected with the Left Kidney and Distal Pancreatectomy: A Case Report Case Reports in Oncology adrenocortical carcinoma tumor thrombus inferior vena cava adjuvant therapy radiotherapy case report |
| title | Adrenocortical Carcinoma with a Renal Vein Thrombus Extending to the Inferior Vena Cava Successfully Resected with the Left Kidney and Distal Pancreatectomy: A Case Report |
| title_full | Adrenocortical Carcinoma with a Renal Vein Thrombus Extending to the Inferior Vena Cava Successfully Resected with the Left Kidney and Distal Pancreatectomy: A Case Report |
| title_fullStr | Adrenocortical Carcinoma with a Renal Vein Thrombus Extending to the Inferior Vena Cava Successfully Resected with the Left Kidney and Distal Pancreatectomy: A Case Report |
| title_full_unstemmed | Adrenocortical Carcinoma with a Renal Vein Thrombus Extending to the Inferior Vena Cava Successfully Resected with the Left Kidney and Distal Pancreatectomy: A Case Report |
| title_short | Adrenocortical Carcinoma with a Renal Vein Thrombus Extending to the Inferior Vena Cava Successfully Resected with the Left Kidney and Distal Pancreatectomy: A Case Report |
| title_sort | adrenocortical carcinoma with a renal vein thrombus extending to the inferior vena cava successfully resected with the left kidney and distal pancreatectomy a case report |
| topic | adrenocortical carcinoma tumor thrombus inferior vena cava adjuvant therapy radiotherapy case report |
| url | https://beta.karger.com/Article/FullText/535367 |
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