Does <i>Helicobacter pylori</i> affect portal hypertensive gastropathy?

<i>Helicobacter pylori (H. pylori)</i> is a major etiological factor of peptic ulcer disease (PUD). It is supposed to be a risk factor for the more frequently encountered PUD in patients with liver cirrhosis. Several investigators have evaluated the effect of <i> H. pylori</i&g...

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Main Author: Al Mofleh Ibrahim
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2007-01-01
Series:The Saudi Journal of Gastroenterology
Subjects:
Online Access:http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2007;volume=13;issue=2;spage=95;epage=97;aulast=Al
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author Al Mofleh Ibrahim
author_facet Al Mofleh Ibrahim
author_sort Al Mofleh Ibrahim
collection DOAJ
description <i>Helicobacter pylori (H. pylori)</i> is a major etiological factor of peptic ulcer disease (PUD). It is supposed to be a risk factor for the more frequently encountered PUD in patients with liver cirrhosis. Several investigators have evaluated the effect of <i> H. pylori</i> on liver cirrhosis, portal hypertensive gastropathy (PHG) and encephalopathy with controversial results. Some reports have shown a higher seroprevalence and suggested a synergistic effect of <i> H. pylori</i> on liver cirrhosis and PHG. However, this increased prevalence is associated with a negative histology and is not influenced by the cause of cirrhosis, PHG, Child class or gender. Most studies have not found any correlation between <i> H. pylori</i> and PHG. In contrast, other studies have reported a markedly lower prevalence of <i> H. pylori</i> in cirrhotics with duodenal ulcer compared to controls. The aim of this article is to review the relationship between <i> H. pylori</i> infection and portal hypertensive gastropathy and the role of <i> H. pylori</i> eradication in cirrhotic patients.
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spelling doaj.art-44074137a6a944f59abe021d176977212022-12-22T00:15:48ZengWolters Kluwer Medknow PublicationsThe Saudi Journal of Gastroenterology1319-37672007-01-011329597Does <i>Helicobacter pylori</i> affect portal hypertensive gastropathy?Al Mofleh Ibrahim<i>Helicobacter pylori (H. pylori)</i> is a major etiological factor of peptic ulcer disease (PUD). It is supposed to be a risk factor for the more frequently encountered PUD in patients with liver cirrhosis. Several investigators have evaluated the effect of <i> H. pylori</i> on liver cirrhosis, portal hypertensive gastropathy (PHG) and encephalopathy with controversial results. Some reports have shown a higher seroprevalence and suggested a synergistic effect of <i> H. pylori</i> on liver cirrhosis and PHG. However, this increased prevalence is associated with a negative histology and is not influenced by the cause of cirrhosis, PHG, Child class or gender. Most studies have not found any correlation between <i> H. pylori</i> and PHG. In contrast, other studies have reported a markedly lower prevalence of <i> H. pylori</i> in cirrhotics with duodenal ulcer compared to controls. The aim of this article is to review the relationship between <i> H. pylori</i> infection and portal hypertensive gastropathy and the role of <i> H. pylori</i> eradication in cirrhotic patients.http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2007;volume=13;issue=2;spage=95;epage=97;aulast=Al<i>H. pylori</i>peptic ulcer diseaseliver cirrhosisportal hypertensive gastropathy
spellingShingle Al Mofleh Ibrahim
Does <i>Helicobacter pylori</i> affect portal hypertensive gastropathy?
The Saudi Journal of Gastroenterology
<i>H. pylori</i>
peptic ulcer disease
liver cirrhosis
portal hypertensive gastropathy
title Does <i>Helicobacter pylori</i> affect portal hypertensive gastropathy?
title_full Does <i>Helicobacter pylori</i> affect portal hypertensive gastropathy?
title_fullStr Does <i>Helicobacter pylori</i> affect portal hypertensive gastropathy?
title_full_unstemmed Does <i>Helicobacter pylori</i> affect portal hypertensive gastropathy?
title_short Does <i>Helicobacter pylori</i> affect portal hypertensive gastropathy?
title_sort does i helicobacter pylori i affect portal hypertensive gastropathy
topic <i>H. pylori</i>
peptic ulcer disease
liver cirrhosis
portal hypertensive gastropathy
url http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2007;volume=13;issue=2;spage=95;epage=97;aulast=Al
work_keys_str_mv AT almoflehibrahim doesihelicobacterpyloriiaffectportalhypertensivegastropathy