Case report: Corticosteroids-induced acute diabetic peripheral neuropathy
A 62-year-old man was diagnosed as IgA nephropathy. He had a pancreatic tumor operation 19 years ago and had a normal plasma glucose test every year. One month after the medication of prednisolone acetate was administered his fasting plasma glucose elevated to 7.1mmol/L while he manifested symptoms...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2022.914325/full |
| _version_ | 1818537397729624064 |
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| author | Jia-Lin Yuan Le Sun Bao-Lin Su Chuang-Xiong Hong |
| author_facet | Jia-Lin Yuan Le Sun Bao-Lin Su Chuang-Xiong Hong |
| author_sort | Jia-Lin Yuan |
| collection | DOAJ |
| description | A 62-year-old man was diagnosed as IgA nephropathy. He had a pancreatic tumor operation 19 years ago and had a normal plasma glucose test every year. One month after the medication of prednisolone acetate was administered his fasting plasma glucose elevated to 7.1mmol/L while he manifested symptoms of thirst, frequent urination, and weight loss. Approximately 3 months after the steroids, he started complaining of numbness, weakness, and muscle cramp in his lower extremities, blood tests showed elevated plasma glucose and electromyography (EMG) revealed impairment of the peripheral nerves in the lower extremity, diabetic peripheral neuropathy was diagnosed. Mecobalamin and Acupuncture were employed and steroids were discontinued, 8 months later he recovered part of his strength and sensation. This case presents a specific adverse drug reaction of corticosteroids that causes diabetes mellitus and subsequently leads to peripheral neuropathy in an acute onset. |
| first_indexed | 2024-12-11T18:50:16Z |
| format | Article |
| id | doaj.art-4407b559f509441bad69ad688457cd45 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-12-11T18:50:16Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-4407b559f509441bad69ad688457cd452022-12-22T00:54:19ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922022-08-011310.3389/fendo.2022.914325914325Case report: Corticosteroids-induced acute diabetic peripheral neuropathyJia-Lin Yuan0Le Sun1Bao-Lin Su2Chuang-Xiong Hong3Cardiovascular Department, Guangzhou University of Chinese Medicine, Guangzhou, ChinaCardiovascular Department, Guangzhou University of Chinese Medicine, Guangzhou, ChinaThe Department of Nephrology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaThe Department of Cardiovascular Disease, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaA 62-year-old man was diagnosed as IgA nephropathy. He had a pancreatic tumor operation 19 years ago and had a normal plasma glucose test every year. One month after the medication of prednisolone acetate was administered his fasting plasma glucose elevated to 7.1mmol/L while he manifested symptoms of thirst, frequent urination, and weight loss. Approximately 3 months after the steroids, he started complaining of numbness, weakness, and muscle cramp in his lower extremities, blood tests showed elevated plasma glucose and electromyography (EMG) revealed impairment of the peripheral nerves in the lower extremity, diabetic peripheral neuropathy was diagnosed. Mecobalamin and Acupuncture were employed and steroids were discontinued, 8 months later he recovered part of his strength and sensation. This case presents a specific adverse drug reaction of corticosteroids that causes diabetes mellitus and subsequently leads to peripheral neuropathy in an acute onset.https://www.frontiersin.org/articles/10.3389/fendo.2022.914325/fullcorticosteroidsIgA nephropathydiabetes mellitusacute diabetic peripheral neuropathyadverse drug reactiondiabetic lumbosacral radiculoplexus neuropathy |
| spellingShingle | Jia-Lin Yuan Le Sun Bao-Lin Su Chuang-Xiong Hong Case report: Corticosteroids-induced acute diabetic peripheral neuropathy Frontiers in Endocrinology corticosteroids IgA nephropathy diabetes mellitus acute diabetic peripheral neuropathy adverse drug reaction diabetic lumbosacral radiculoplexus neuropathy |
| title | Case report: Corticosteroids-induced acute diabetic peripheral neuropathy |
| title_full | Case report: Corticosteroids-induced acute diabetic peripheral neuropathy |
| title_fullStr | Case report: Corticosteroids-induced acute diabetic peripheral neuropathy |
| title_full_unstemmed | Case report: Corticosteroids-induced acute diabetic peripheral neuropathy |
| title_short | Case report: Corticosteroids-induced acute diabetic peripheral neuropathy |
| title_sort | case report corticosteroids induced acute diabetic peripheral neuropathy |
| topic | corticosteroids IgA nephropathy diabetes mellitus acute diabetic peripheral neuropathy adverse drug reaction diabetic lumbosacral radiculoplexus neuropathy |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2022.914325/full |
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