Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-β Signaling in Developing Skin Vasculature

Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-β Signaling in Developing Skin Vasculature

Mural cells (pericytes and vascular smooth muscle cells) are essential for the regulation of vascular networks and maintenance of vascular integrity, but their origins are diverse in different tissues and not known in the organs that arise from the ectoderm, such as skin. Here, we show that tissue-l...

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Bibliographic Details
Main Authors: Tomoko Yamazaki, Ani Nalbandian, Yutaka Uchida, Wenling Li, Thomas D. Arnold, Yoshiaki Kubota, Seiji Yamamoto, Masatsugu Ema, Yoh-suke Mukouyama
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Cell Reports
Subjects:
mural cell
pericyte
myeloid
tissue macrophage
TGF-β
fate mapping
skin
brain
capillary blood vessel
vascular development
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717302875

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