ANTIDIARRHOEAL ACTIVITY OF LEAF EXTRACT OF CELOSIA ARGENTEA IN EXPERIMENTALLY INDUCED DIARRHOEA IN RATS
In order to scientifically apprise some of the anecdotal, folkloric, ethno medicaluses of celosia argentea, the present study was undertaken to examine the antidiarrhoealproperties of alcoholic extract of leaves of Celosia argentea on diarrhoea by usingdifferent experimental models. Anti-diarrhoeal...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2010-03-01
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| Series: | Journal of Advanced Pharmaceutical Technology & Research |
| Subjects: | |
| Online Access: | http://122.168.195.169/Online%20Admission/CourseInstr.aspx?STS=4&MID=46&Title=Antidiarrhoeal%20activity%20of%20leaf%20extract%20of%20Celosia%20argentea%20in%20experimentally%20induced%20diarrhoea%20in%20rats |
| _version_ | 1818198222157381632 |
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| author | Santosh Ghule Sunder Singh Gali Vidyasagar Praveen Sharma Bimlesh Kumar |
| author_facet | Santosh Ghule Sunder Singh Gali Vidyasagar Praveen Sharma Bimlesh Kumar |
| author_sort | Santosh Ghule |
| collection | DOAJ |
| description | In order to scientifically apprise some of the anecdotal, folkloric, ethno medicaluses of celosia argentea, the present study was undertaken to examine the antidiarrhoealproperties of alcoholic extract of leaves of Celosia argentea on diarrhoea by usingdifferent experimental models. Anti-diarrhoeal effect was evaluated by castor oil induceddiarrhoea, charcoal meal test and PGE2 induced diarrhoea. Loperamide (2 mg/kg) andatropine (0.1mg/kg) were used as standard drugs. Extract was used in 100 and 200 mg/kgdose. It produced dose related anti-diarrhoeal effect. Results suggest that it may actcentrally and may inhibit the PGE2 to give anti-diarrhoeal effects. Result of charcoal mealtest also suggests its anti-muscarinic activity. |
| first_indexed | 2024-12-12T02:02:26Z |
| format | Article |
| id | doaj.art-440dca0c284d40078a5157cbfbc0ce88 |
| institution | Directory Open Access Journal |
| issn | 0976-2094 |
| language | English |
| last_indexed | 2024-12-12T02:02:26Z |
| publishDate | 2010-03-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Advanced Pharmaceutical Technology & Research |
| spelling | doaj.art-440dca0c284d40078a5157cbfbc0ce882022-12-22T00:42:08ZengWolters Kluwer Medknow PublicationsJournal of Advanced Pharmaceutical Technology & Research0976-20942010-03-01114148ANTIDIARRHOEAL ACTIVITY OF LEAF EXTRACT OF CELOSIA ARGENTEA IN EXPERIMENTALLY INDUCED DIARRHOEA IN RATSSantosh GhuleSunder SinghGali VidyasagarPraveen SharmaBimlesh KumarIn order to scientifically apprise some of the anecdotal, folkloric, ethno medicaluses of celosia argentea, the present study was undertaken to examine the antidiarrhoealproperties of alcoholic extract of leaves of Celosia argentea on diarrhoea by usingdifferent experimental models. Anti-diarrhoeal effect was evaluated by castor oil induceddiarrhoea, charcoal meal test and PGE2 induced diarrhoea. Loperamide (2 mg/kg) andatropine (0.1mg/kg) were used as standard drugs. Extract was used in 100 and 200 mg/kgdose. It produced dose related anti-diarrhoeal effect. Results suggest that it may actcentrally and may inhibit the PGE2 to give anti-diarrhoeal effects. Result of charcoal mealtest also suggests its anti-muscarinic activity.http://122.168.195.169/Online%20Admission/CourseInstr.aspx?STS=4&MID=46&Title=Antidiarrhoeal%20activity%20of%20leaf%20extract%20of%20Celosia%20argentea%20in%20experimentally%20induced%20diarrhoea%20in%20ratsCelosia argenteacastor oil diarrhoeacharcoal mealPGE2 |
| spellingShingle | Santosh Ghule Sunder Singh Gali Vidyasagar Praveen Sharma Bimlesh Kumar ANTIDIARRHOEAL ACTIVITY OF LEAF EXTRACT OF CELOSIA ARGENTEA IN EXPERIMENTALLY INDUCED DIARRHOEA IN RATS Journal of Advanced Pharmaceutical Technology & Research Celosia argentea castor oil diarrhoea charcoal meal PGE2 |
| title | ANTIDIARRHOEAL ACTIVITY OF LEAF EXTRACT OF CELOSIA ARGENTEA IN EXPERIMENTALLY INDUCED DIARRHOEA IN RATS |
| title_full | ANTIDIARRHOEAL ACTIVITY OF LEAF EXTRACT OF CELOSIA ARGENTEA IN EXPERIMENTALLY INDUCED DIARRHOEA IN RATS |
| title_fullStr | ANTIDIARRHOEAL ACTIVITY OF LEAF EXTRACT OF CELOSIA ARGENTEA IN EXPERIMENTALLY INDUCED DIARRHOEA IN RATS |
| title_full_unstemmed | ANTIDIARRHOEAL ACTIVITY OF LEAF EXTRACT OF CELOSIA ARGENTEA IN EXPERIMENTALLY INDUCED DIARRHOEA IN RATS |
| title_short | ANTIDIARRHOEAL ACTIVITY OF LEAF EXTRACT OF CELOSIA ARGENTEA IN EXPERIMENTALLY INDUCED DIARRHOEA IN RATS |
| title_sort | antidiarrhoeal activity of leaf extract of celosia argentea in experimentally induced diarrhoea in rats |
| topic | Celosia argentea castor oil diarrhoea charcoal meal PGE2 |
| url | http://122.168.195.169/Online%20Admission/CourseInstr.aspx?STS=4&MID=46&Title=Antidiarrhoeal%20activity%20of%20leaf%20extract%20of%20Celosia%20argentea%20in%20experimentally%20induced%20diarrhoea%20in%20rats |
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