NEW OPPORTUNITIES IN TREATMENT OF SEVERE SYSTEMIC TYPE OF JUVENILE ARTHRITIS
<em>The article presents a case report of a severe clinical course of systemic type of juvenile arthritis, resistant to treatment with corticosteroids and classic immunosuppressive agents in girl 9 years old. Biological agent — tocilizumab showed beneficial effect: exudative lesions of joints,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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"Paediatrician" Publishers LLC
2010-01-01
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| Series: | Вопросы современной педиатрии |
| Online Access: | http://vsp.spr-journal.ru:80/jour/article/view/937 |
| Summary: | <em>The article presents a case report of a severe clinical course of systemic type of juvenile arthritis, resistant to treatment with corticosteroids and classic immunosuppressive agents in girl 9 years old. Biological agent — tocilizumab showed beneficial effect: exudative lesions of joints, morning joint stiffness stopped and the range of motions restored in almost all affected joints in 8 weeks of treatment. A girl became more active, her emotional state improved. Laboratory signs of disease’s activity (ESR, concentration of C-reactive protein in plasma) were normalized in 4 weeks. The drug induced development of clinical and laboratory remission of a disease.</em><br /><strong><em>Key words: children, juvenile arthritis, treatment, tocilizumab.</em></strong><br /><span style="text-decoration: underline;"><em>(<em><em>Voprosy sovremennoi pediatrii — </em></em>Current Pediatrics. – 2010;9(4):<em><span>160-167</span></em>)</em></span> |
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| ISSN: | 1682-5527 1682-5535 |