Diagnostic possibilities of using micro-RNA for kidney transplantation
Allogeneic kidney transplantation is the optimal approach for the treatment of patients with terminal stage of chronic kidney disease. Moreover, post-transplant monitoring and optimization of immunosuppressive therapy with early non-invasive molecular-biological markers can significantly improve t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2018-09-01
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| Series: | Vestnik Transplantologii i Iskusstvennyh Organov |
| Subjects: | |
| Online Access: | https://journal.transpl.ru/vtio/article/view/917 |
| _version_ | 1797871991598874624 |
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| author | I. A. Pirozhkov M. E. Malyshev O. N. Reznik V. A. Manukovsky A. E. Skvortsov |
| author_facet | I. A. Pirozhkov M. E. Malyshev O. N. Reznik V. A. Manukovsky A. E. Skvortsov |
| author_sort | I. A. Pirozhkov |
| collection | DOAJ |
| description | Allogeneic kidney transplantation is the optimal approach for the treatment of patients with terminal stage of chronic kidney disease. Moreover, post-transplant monitoring and optimization of immunosuppressive therapy with early non-invasive molecular-biological markers can significantly improve the long-term outcome of transplantation. As markers of damage to the kidney transplant, it is proposed to use micro-RNAs that play a fundamental role in the regulation of the activity of various genes. The level of expression of micro-RNA in different tissues can correlate with certain pathological conditions. In this review, the literature data on the study of the perspectives for the use of micro-RNA as biomarkers of the post-transplantation period in kidney transplant recipients are considered. |
| first_indexed | 2024-04-10T00:51:48Z |
| format | Article |
| id | doaj.art-4417cbea933740a6b25f8cf0379fb894 |
| institution | Directory Open Access Journal |
| issn | 1995-1191 |
| language | Russian |
| last_indexed | 2024-04-10T00:51:48Z |
| publishDate | 2018-09-01 |
| publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
| record_format | Article |
| series | Vestnik Transplantologii i Iskusstvennyh Organov |
| spelling | doaj.art-4417cbea933740a6b25f8cf0379fb8942023-03-13T10:37:25ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovVestnik Transplantologii i Iskusstvennyh Organov1995-11912018-09-01203879410.15825/1995-1191-2018-3-87-94726Diagnostic possibilities of using micro-RNA for kidney transplantationI. A. Pirozhkov0M. E. Malyshev1O. N. Reznik2V. A. Manukovsky3A. E. Skvortsov4Saint-Petersburg I.I. Dzhanelidze State Research Institute of Emergency MedicineSaint-Petersburg I.I. Dzhanelidze State Research Institute of Emergency MedicineSaint-Petersburg I.I. Dzhanelidze State Research Institute of Emergency MedicineSaint-Petersburg I.I. Dzhanelidze State Research Institute of Emergency MedicineSaint-Petersburg I.I. Dzhanelidze State Research Institute of Emergency MedicineAllogeneic kidney transplantation is the optimal approach for the treatment of patients with terminal stage of chronic kidney disease. Moreover, post-transplant monitoring and optimization of immunosuppressive therapy with early non-invasive molecular-biological markers can significantly improve the long-term outcome of transplantation. As markers of damage to the kidney transplant, it is proposed to use micro-RNAs that play a fundamental role in the regulation of the activity of various genes. The level of expression of micro-RNA in different tissues can correlate with certain pathological conditions. In this review, the literature data on the study of the perspectives for the use of micro-RNA as biomarkers of the post-transplantation period in kidney transplant recipients are considered.https://journal.transpl.ru/vtio/article/view/917micro-rnakidney transplantationacute kidney injuryacute allograft rejection |
| spellingShingle | I. A. Pirozhkov M. E. Malyshev O. N. Reznik V. A. Manukovsky A. E. Skvortsov Diagnostic possibilities of using micro-RNA for kidney transplantation Vestnik Transplantologii i Iskusstvennyh Organov micro-rna kidney transplantation acute kidney injury acute allograft rejection |
| title | Diagnostic possibilities of using micro-RNA for kidney transplantation |
| title_full | Diagnostic possibilities of using micro-RNA for kidney transplantation |
| title_fullStr | Diagnostic possibilities of using micro-RNA for kidney transplantation |
| title_full_unstemmed | Diagnostic possibilities of using micro-RNA for kidney transplantation |
| title_short | Diagnostic possibilities of using micro-RNA for kidney transplantation |
| title_sort | diagnostic possibilities of using micro rna for kidney transplantation |
| topic | micro-rna kidney transplantation acute kidney injury acute allograft rejection |
| url | https://journal.transpl.ru/vtio/article/view/917 |
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