Elevation of intact and proteolytic fragments of acute phase proteins constitutes the earliest systemic antiviral response in HIV-1 infection.

Elevation of intact and proteolytic fragments of acute phase proteins constitutes the earliest systemic antiviral response in HIV-1 infection.

The earliest immune responses activated in acute human immunodeficiency virus type 1 infection (AHI) exert a critical influence on subsequent virus spread or containment. During this time frame, components of the innate immune system such as macrophages and DCs, NK cells, beta-defensins, complement...

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Main Authors: Holger B Kramer, Kerry J Lavender, Li Qin, Andrea R Stacey, Michael K P Liu, Katalin di Gleria, Alison Simmons, Nancy Gasper-Smith, Barton F Haynes, Andrew J McMichael, Persephone Borrow, Benedikt M Kessler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20463814/pdf/?tool=EBI

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