Hypoxia and Extracellular Acidification as Drivers of Melanoma Progression and Drug Resistance

Hypoxia and Extracellular Acidification as Drivers of Melanoma Progression and Drug Resistance

Hypoxia and elevated extracellular acidification are prevalent features of solid tumors and they are often shown to facilitate cancer progression and drug resistance. In this review, we have compiled recent and most relevant research pertaining to the role of hypoxia and acidification in melanoma gr...

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Bibliographic Details
Main Authors: Ewelina Dratkiewicz, Aleksandra Simiczyjew, Justyna Mazurkiewicz, Marcin Ziętek, Rafał Matkowski, Dorota Nowak
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
melanoma
hypoxia
acidification
drug resistance
tumor microenvironment
immune escape
Online Access:https://www.mdpi.com/2073-4409/10/4/862

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