Gamma-band synchronisation in a frontotemporal auditory information processing network
Neural oscillations are fundamental mechanisms of the human brain that enable coordinated activity of different brain regions during perceptual and cognitive processes. A frontotemporal network generated by means of gamma oscillations and comprising the auditory cortex (AC) and the anterior cingulat...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-10-01
|
| Series: | NeuroImage |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1053811921005838 |
| _version_ | 1819114389057306624 |
|---|---|
| author | Gregor Leicht Jonas Björklund Sebastian Vauth Marius Mußmann Moritz Haaf Saskia Steinmann Jonas Rauh Christoph Mulert |
| author_facet | Gregor Leicht Jonas Björklund Sebastian Vauth Marius Mußmann Moritz Haaf Saskia Steinmann Jonas Rauh Christoph Mulert |
| author_sort | Gregor Leicht |
| collection | DOAJ |
| description | Neural oscillations are fundamental mechanisms of the human brain that enable coordinated activity of different brain regions during perceptual and cognitive processes. A frontotemporal network generated by means of gamma oscillations and comprising the auditory cortex (AC) and the anterior cingulate cortex (ACC) has been shown to be involved in the cognitively demanding auditory information processing. This study aims to reveal patterns of functional and effective connectivity within this network in healthy subjects by means of simultaneously recorded electroencephalography (EEG) and functional magnetic resonance imaging (fMRI).We simultaneously recorded EEG and fMRI in 28 healthy subjects during the performance of a cognitively demanding auditory choice reaction task. Connectivity between the ACC and AC was analysed employing EEG and fMRI connectivity measures.We found a significant BOLD signal correlation between the ACC and AC, a significant task-dependant increase of fMRI connectivity (gPPI) and a significant increase in functional coupling in the gamma frequency range between these regions (LPS), which was increased in top-down direction (granger analysis). EEG and fMRI connectivity measures were positively correlated.The results of these study point to a role of a top-down influence of the ACC on the AC executed by means of gamma synchronisation. The replication of fMRI connectivity patterns in simultaneously recorded EEG data and the correlation between connectivity measures from both domains found in our study show, that brain connectivity based on the synchronisation of gamma oscillations is mirrored in fMRI connectivity patterns. |
| first_indexed | 2024-12-22T04:44:31Z |
| format | Article |
| id | doaj.art-4418c7b466ff405cb53e4a5b330489b7 |
| institution | Directory Open Access Journal |
| issn | 1095-9572 |
| language | English |
| last_indexed | 2024-12-22T04:44:31Z |
| publishDate | 2021-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage |
| spelling | doaj.art-4418c7b466ff405cb53e4a5b330489b72022-12-21T18:38:38ZengElsevierNeuroImage1095-95722021-10-01239118307Gamma-band synchronisation in a frontotemporal auditory information processing networkGregor Leicht0Jonas Björklund1Sebastian Vauth2Marius Mußmann3Moritz Haaf4Saskia Steinmann5Jonas Rauh6Christoph Mulert7Department of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch (PNB), University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg D-20246, Germany; Corresponding author.Department of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch (PNB), University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg D-20246, GermanyDepartment of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch (PNB), University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg D-20246, GermanyDepartment of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch (PNB), University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg D-20246, GermanyDepartment of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch (PNB), University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg D-20246, GermanyDepartment of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch (PNB), University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg D-20246, GermanyDepartment of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch (PNB), University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg D-20246, GermanyDepartment of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch (PNB), University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg D-20246, Germany; Center of Psychiatry, Justus-Liebig University, Giessen, GermanyNeural oscillations are fundamental mechanisms of the human brain that enable coordinated activity of different brain regions during perceptual and cognitive processes. A frontotemporal network generated by means of gamma oscillations and comprising the auditory cortex (AC) and the anterior cingulate cortex (ACC) has been shown to be involved in the cognitively demanding auditory information processing. This study aims to reveal patterns of functional and effective connectivity within this network in healthy subjects by means of simultaneously recorded electroencephalography (EEG) and functional magnetic resonance imaging (fMRI).We simultaneously recorded EEG and fMRI in 28 healthy subjects during the performance of a cognitively demanding auditory choice reaction task. Connectivity between the ACC and AC was analysed employing EEG and fMRI connectivity measures.We found a significant BOLD signal correlation between the ACC and AC, a significant task-dependant increase of fMRI connectivity (gPPI) and a significant increase in functional coupling in the gamma frequency range between these regions (LPS), which was increased in top-down direction (granger analysis). EEG and fMRI connectivity measures were positively correlated.The results of these study point to a role of a top-down influence of the ACC on the AC executed by means of gamma synchronisation. The replication of fMRI connectivity patterns in simultaneously recorded EEG data and the correlation between connectivity measures from both domains found in our study show, that brain connectivity based on the synchronisation of gamma oscillations is mirrored in fMRI connectivity patterns.http://www.sciencedirect.com/science/article/pii/S1053811921005838Auditory cortexAnterior cingulate cortexSimultaneous EEG and fMRILagged phase synchronisationGranger causality analysisGeneralized psychophysiological interaction |
| spellingShingle | Gregor Leicht Jonas Björklund Sebastian Vauth Marius Mußmann Moritz Haaf Saskia Steinmann Jonas Rauh Christoph Mulert Gamma-band synchronisation in a frontotemporal auditory information processing network NeuroImage Auditory cortex Anterior cingulate cortex Simultaneous EEG and fMRI Lagged phase synchronisation Granger causality analysis Generalized psychophysiological interaction |
| title | Gamma-band synchronisation in a frontotemporal auditory information processing network |
| title_full | Gamma-band synchronisation in a frontotemporal auditory information processing network |
| title_fullStr | Gamma-band synchronisation in a frontotemporal auditory information processing network |
| title_full_unstemmed | Gamma-band synchronisation in a frontotemporal auditory information processing network |
| title_short | Gamma-band synchronisation in a frontotemporal auditory information processing network |
| title_sort | gamma band synchronisation in a frontotemporal auditory information processing network |
| topic | Auditory cortex Anterior cingulate cortex Simultaneous EEG and fMRI Lagged phase synchronisation Granger causality analysis Generalized psychophysiological interaction |
| url | http://www.sciencedirect.com/science/article/pii/S1053811921005838 |
| work_keys_str_mv | AT gregorleicht gammabandsynchronisationinafrontotemporalauditoryinformationprocessingnetwork AT jonasbjorklund gammabandsynchronisationinafrontotemporalauditoryinformationprocessingnetwork AT sebastianvauth gammabandsynchronisationinafrontotemporalauditoryinformationprocessingnetwork AT mariusmußmann gammabandsynchronisationinafrontotemporalauditoryinformationprocessingnetwork AT moritzhaaf gammabandsynchronisationinafrontotemporalauditoryinformationprocessingnetwork AT saskiasteinmann gammabandsynchronisationinafrontotemporalauditoryinformationprocessingnetwork AT jonasrauh gammabandsynchronisationinafrontotemporalauditoryinformationprocessingnetwork AT christophmulert gammabandsynchronisationinafrontotemporalauditoryinformationprocessingnetwork |