Effect of metformin on left ventricular mass and functional parameters in non-diabetic patients: a meta-analysis of randomized clinical trials
Highlights 1. Metformin therapy regresses LVH by approximately 10 g/m2 in non-diabetic patients after 12 months of use (SMCC = −0.63, 95% CI − 1.23; − 0.04, p = 0.04). 2. Metformin therapy was associated with a modest (2–3%) but greater overall improvement in LVEF. 3. Higher dose (> 1000 mg/day)...
Main Authors: | Ahmed M. Kamel, Nirmeen Sabry, Samar Farid |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-09-01
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Series: | BMC Cardiovascular Disorders |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12872-022-02845-w |
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