Comparison of metabolic syndrome components, inflammation and oxidative stress indices in normal weight obese and normal weight women: A case- control study
Background: Normal Body Mass Index (BMI) = 18.5-24.9 kg/m2 and high Body Fat (BF), have been defined as Normal Weigh Obesity (NWO), which can increase the risk of Metabolic Syndrome (MetS) and cardiovascular diseases. The present study aimed to determine the association between NWO and MetS indicato...
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2018-07-01
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| Series: | Journal of Health Sciences and Surveillance System |
| Subjects: | |
| Online Access: | http://jhsss.sums.ac.ir/article_45918_817be5ab69e2676ac30637fe36903006.pdf |
| _version_ | 1818216223808159744 |
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| author | Mohammad Hassan Eftekhari Maryam Ranjbar Zahedani Atefeh Kohansal |
| author_facet | Mohammad Hassan Eftekhari Maryam Ranjbar Zahedani Atefeh Kohansal |
| author_sort | Mohammad Hassan Eftekhari |
| collection | DOAJ |
| description | Background: Normal Body Mass Index (BMI) = 18.5-24.9 kg/m2 and high Body Fat (BF), have been defined as Normal Weigh Obesity (NWO), which can increase the risk of Metabolic Syndrome (MetS) and cardiovascular diseases. The present study aimed to determine the association between NWO and MetS indicators, Insulin Resistance (IR), and inflammatory and oxidative stress indices in NW obese compared to normal weight women referring to Imam Reza medical center, Shiraz, Iran.<br /> Methods: In this case-control study, 41 healthy NW obese Iranian women were recruited and compared to 45 healthy non-obese control subjects. Anthropometric features, body composition, blood pressure, inflammation and oxidative stress indices, fasting insulin, lipid profile, and blood sugar were measured. IR was also assessed by means of special formulas.<br /> Results: The results showed a significant difference between the NWO and the control group regarding anthropometric measurements and body composition, including waist (p=0.008) and hip (p<0.001) circumferences, BF (p<0.001), skeletal muscle (p=0.03), protein(p=0.04), body cell mass(p=0.02), bone mass content(p=0.04), and arm circumference(p<0.001). All subjects had normal systolic and diastolic blood pressures. However, the NWO group showed significantly higher serum concentrations of triglycerides (p=0.02), total cholesterol(p=0.02), and C-reactive protein (p<0.001). On the other hand, the results of McAuley test indicated significantly lower insulin sensitivity in the NWO group (p=0.03). Besides, serum MDA concentration did not have a marked differences in both study groups. <br /> Conclusion: |
| first_indexed | 2024-12-12T06:48:34Z |
| format | Article |
| id | doaj.art-441a9bd05d73406ca1f6477a12306eb8 |
| institution | Directory Open Access Journal |
| issn | 2345-2218 2345-3893 |
| language | English |
| last_indexed | 2024-12-12T06:48:34Z |
| publishDate | 2018-07-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Journal of Health Sciences and Surveillance System |
| spelling | doaj.art-441a9bd05d73406ca1f6477a12306eb82022-12-22T00:34:06ZengShiraz University of Medical SciencesJournal of Health Sciences and Surveillance System2345-22182345-38932018-07-016311612210.30476/jhsss.2019.84627.103645918Comparison of metabolic syndrome components, inflammation and oxidative stress indices in normal weight obese and normal weight women: A case- control studyMohammad Hassan Eftekhari0Maryam Ranjbar Zahedani1Atefeh Kohansal2PhD in nutrition sciences, Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.PhD candidate in nutrition sciences, Student research committee, Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.MSc student in nutrition sciences, Student research committee, Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.Background: Normal Body Mass Index (BMI) = 18.5-24.9 kg/m2 and high Body Fat (BF), have been defined as Normal Weigh Obesity (NWO), which can increase the risk of Metabolic Syndrome (MetS) and cardiovascular diseases. The present study aimed to determine the association between NWO and MetS indicators, Insulin Resistance (IR), and inflammatory and oxidative stress indices in NW obese compared to normal weight women referring to Imam Reza medical center, Shiraz, Iran.<br /> Methods: In this case-control study, 41 healthy NW obese Iranian women were recruited and compared to 45 healthy non-obese control subjects. Anthropometric features, body composition, blood pressure, inflammation and oxidative stress indices, fasting insulin, lipid profile, and blood sugar were measured. IR was also assessed by means of special formulas.<br /> Results: The results showed a significant difference between the NWO and the control group regarding anthropometric measurements and body composition, including waist (p=0.008) and hip (p<0.001) circumferences, BF (p<0.001), skeletal muscle (p=0.03), protein(p=0.04), body cell mass(p=0.02), bone mass content(p=0.04), and arm circumference(p<0.001). All subjects had normal systolic and diastolic blood pressures. However, the NWO group showed significantly higher serum concentrations of triglycerides (p=0.02), total cholesterol(p=0.02), and C-reactive protein (p<0.001). On the other hand, the results of McAuley test indicated significantly lower insulin sensitivity in the NWO group (p=0.03). Besides, serum MDA concentration did not have a marked differences in both study groups. <br /> Conclusion:http://jhsss.sums.ac.ir/article_45918_817be5ab69e2676ac30637fe36903006.pdfobesityadipose tissuemetabolic syndromeinsulin resistance |
| spellingShingle | Mohammad Hassan Eftekhari Maryam Ranjbar Zahedani Atefeh Kohansal Comparison of metabolic syndrome components, inflammation and oxidative stress indices in normal weight obese and normal weight women: A case- control study Journal of Health Sciences and Surveillance System obesity adipose tissue metabolic syndrome insulin resistance |
| title | Comparison of metabolic syndrome components, inflammation and oxidative stress indices in normal weight obese and normal weight women: A case- control study |
| title_full | Comparison of metabolic syndrome components, inflammation and oxidative stress indices in normal weight obese and normal weight women: A case- control study |
| title_fullStr | Comparison of metabolic syndrome components, inflammation and oxidative stress indices in normal weight obese and normal weight women: A case- control study |
| title_full_unstemmed | Comparison of metabolic syndrome components, inflammation and oxidative stress indices in normal weight obese and normal weight women: A case- control study |
| title_short | Comparison of metabolic syndrome components, inflammation and oxidative stress indices in normal weight obese and normal weight women: A case- control study |
| title_sort | comparison of metabolic syndrome components inflammation and oxidative stress indices in normal weight obese and normal weight women a case control study |
| topic | obesity adipose tissue metabolic syndrome insulin resistance |
| url | http://jhsss.sums.ac.ir/article_45918_817be5ab69e2676ac30637fe36903006.pdf |
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