Paraneoplastic Neurological Syndromes: Study of Prevalence in a Province of the Lombardy Region, Italy
Paraneoplastic neurological syndromes (PNSs) are a heterogeneous group of rare immune-mediated diseases associated with cancer. The aim of this study was to investigate the prevalence of PNSs in the province of Brescia. PNS prevalence was calculated using the Lombardy regional hospital admission rec...
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MDPI AG
2020-09-01
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| Series: | Journal of Clinical Medicine |
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| author | Lorenzo Lorusso Vincenza Precone Daniela Ferrari Gaelle K. Ngonga Antonio Giampiero Russo Stefano Paolacci Matteo Bertelli |
| author_facet | Lorenzo Lorusso Vincenza Precone Daniela Ferrari Gaelle K. Ngonga Antonio Giampiero Russo Stefano Paolacci Matteo Bertelli |
| author_sort | Lorenzo Lorusso |
| collection | DOAJ |
| description | Paraneoplastic neurological syndromes (PNSs) are a heterogeneous group of rare immune-mediated diseases associated with cancer. The aim of this study was to investigate the prevalence of PNSs in the province of Brescia. PNS prevalence was calculated using the Lombardy regional hospital admission records from 1998 to 2003. We used the website “Epidemiologic and Economic Atlas of Hospital Activities in Lombardy” and the “International Statistical Classification of Diseases and Related Health Problems”. In the province of Brescia, we found 54 cases of PNSs, 29 with subacute neuropathies, five with paraneoplastic cerebellar degeneration and 20 with encephalomyelitis. Peripheral nervous system diseases were the most frequent neurological disorders. In Lombardy, the number of PNS patients admitted was 322 (133 with encephalomyelitis, 21 with paraneoplastic cerebellar degeneration, 166 with polyneuropathies and two with optic degeneration). In Lombardy, the prevalence of PNSs was 25 in 100,000 hospital admissions and 5.92 in 100,000 for the Lombardy population. Our results show a discrete presence of PNS patients in the province of Brescia and in the Lombardy region as a whole. |
| first_indexed | 2024-03-10T16:02:34Z |
| format | Article |
| id | doaj.art-441b262822394bafb2db91d2d5a9c12a |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T16:02:34Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
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| spelling | doaj.art-441b262822394bafb2db91d2d5a9c12a2023-11-20T15:10:06ZengMDPI AGJournal of Clinical Medicine2077-03832020-09-01910310510.3390/jcm9103105Paraneoplastic Neurological Syndromes: Study of Prevalence in a Province of the Lombardy Region, ItalyLorenzo Lorusso0Vincenza Precone1Daniela Ferrari2Gaelle K. Ngonga3Antonio Giampiero Russo4Stefano Paolacci5Matteo Bertelli6ASST Lecco, UOC Neurology and Stroke Unit, 23807 Merate (LC), ItalyMAGI EUREGIO, 39100 Bolzano, ItalyDepartment of Neurology, Simone Veil Hospital, 95600 Eaubonne, FranceDepartment of Neurology, Hospital Centre Emile Mayrisch, Esch-sur-Alzette, 4240 Luxembourg, LuxembourgUOC Unità di Epidemiologia, ATS della Città Metropolitana di Milano, 20122 Milan, ItalyMAGI’S LAB, 38068 Rovereto (TN), ItalyMAGI EUREGIO, 39100 Bolzano, ItalyParaneoplastic neurological syndromes (PNSs) are a heterogeneous group of rare immune-mediated diseases associated with cancer. The aim of this study was to investigate the prevalence of PNSs in the province of Brescia. PNS prevalence was calculated using the Lombardy regional hospital admission records from 1998 to 2003. We used the website “Epidemiologic and Economic Atlas of Hospital Activities in Lombardy” and the “International Statistical Classification of Diseases and Related Health Problems”. In the province of Brescia, we found 54 cases of PNSs, 29 with subacute neuropathies, five with paraneoplastic cerebellar degeneration and 20 with encephalomyelitis. Peripheral nervous system diseases were the most frequent neurological disorders. In Lombardy, the number of PNS patients admitted was 322 (133 with encephalomyelitis, 21 with paraneoplastic cerebellar degeneration, 166 with polyneuropathies and two with optic degeneration). In Lombardy, the prevalence of PNSs was 25 in 100,000 hospital admissions and 5.92 in 100,000 for the Lombardy population. Our results show a discrete presence of PNS patients in the province of Brescia and in the Lombardy region as a whole.https://www.mdpi.com/2077-0383/9/10/3105paraneoplastic neurological syndromecancerPNS prevalencePNS epidemiology |
| spellingShingle | Lorenzo Lorusso Vincenza Precone Daniela Ferrari Gaelle K. Ngonga Antonio Giampiero Russo Stefano Paolacci Matteo Bertelli Paraneoplastic Neurological Syndromes: Study of Prevalence in a Province of the Lombardy Region, Italy Journal of Clinical Medicine paraneoplastic neurological syndrome cancer PNS prevalence PNS epidemiology |
| title | Paraneoplastic Neurological Syndromes: Study of Prevalence in a Province of the Lombardy Region, Italy |
| title_full | Paraneoplastic Neurological Syndromes: Study of Prevalence in a Province of the Lombardy Region, Italy |
| title_fullStr | Paraneoplastic Neurological Syndromes: Study of Prevalence in a Province of the Lombardy Region, Italy |
| title_full_unstemmed | Paraneoplastic Neurological Syndromes: Study of Prevalence in a Province of the Lombardy Region, Italy |
| title_short | Paraneoplastic Neurological Syndromes: Study of Prevalence in a Province of the Lombardy Region, Italy |
| title_sort | paraneoplastic neurological syndromes study of prevalence in a province of the lombardy region italy |
| topic | paraneoplastic neurological syndrome cancer PNS prevalence PNS epidemiology |
| url | https://www.mdpi.com/2077-0383/9/10/3105 |
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