Natural Bioactive Molecules: An Alternative Approach to the Treatment and Control of COVID-19
Several coronaviruses (CoVs) have been associated with serious health hazards in recent decades, resulting in the deaths of thousands around the globe. The recent coronavirus pandemic has emphasized the importance of discovering novel and effective antiviral medicines as quickly as possible to preve...
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-11-01
|
| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/22/23/12638 |
| _version_ | 1797507768655020032 |
|---|---|
| author | Fahadul Islam Shabana Bibi Atkia Farzana Khan Meem Md. Mohaimenul Islam Md. Saidur Rahaman Sristy Bepary Md. Mizanur Rahman Md. Mominur Rahman Amin Elzaki Samih Kajoak Hamid Osman Mohamed ElSamani Mayeen Uddin Khandaker Abubakr M. Idris Talha Bin Emran |
| author_facet | Fahadul Islam Shabana Bibi Atkia Farzana Khan Meem Md. Mohaimenul Islam Md. Saidur Rahaman Sristy Bepary Md. Mizanur Rahman Md. Mominur Rahman Amin Elzaki Samih Kajoak Hamid Osman Mohamed ElSamani Mayeen Uddin Khandaker Abubakr M. Idris Talha Bin Emran |
| author_sort | Fahadul Islam |
| collection | DOAJ |
| description | Several coronaviruses (CoVs) have been associated with serious health hazards in recent decades, resulting in the deaths of thousands around the globe. The recent coronavirus pandemic has emphasized the importance of discovering novel and effective antiviral medicines as quickly as possible to prevent more loss of human lives. Positive-sense RNA viruses with group spikes protruding from their surfaces and an abnormally large RNA genome enclose CoVs. CoVs have already been related to a range of respiratory infectious diseases possibly fatal to humans, such as MERS, SARS, and the current COVID-19 outbreak. As a result, effective prevention, treatment, and medications against human coronavirus (HCoV) is urgently needed. In recent years, many natural substances have been discovered with a variety of biological significance, including antiviral properties. Throughout this work, we reviewed a wide range of natural substances that interrupt the life cycles for MERS and SARS, as well as their potential application in the treatment of COVID-19. |
| first_indexed | 2024-03-10T04:53:09Z |
| format | Article |
| id | doaj.art-4420087084a34319b9357afdd128b74a |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T04:53:09Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-4420087084a34319b9357afdd128b74a2023-11-23T02:25:33ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-11-0122231263810.3390/ijms222312638Natural Bioactive Molecules: An Alternative Approach to the Treatment and Control of COVID-19Fahadul Islam0Shabana Bibi1Atkia Farzana Khan Meem2Md. Mohaimenul Islam3Md. Saidur Rahaman4Sristy Bepary5Md. Mizanur Rahman6Md. Mominur Rahman7Amin Elzaki8Samih Kajoak9Hamid Osman10Mohamed ElSamani11Mayeen Uddin Khandaker12Abubakr M. Idris13Talha Bin Emran14Department of Pharmacy, Daffodil International University, Dhaka 1207, BangladeshYunnan Herbal Laboratory, College of Ecology and Environmental Sciences, Yunnan University, Kunming 650091, ChinaDepartment of Pharmacy, Daffodil International University, Dhaka 1207, BangladeshDepartment of Pharmacy, Daffodil International University, Dhaka 1207, BangladeshDepartment of Pharmacy, Daffodil International University, Dhaka 1207, BangladeshDepartment of Pharmacy, Daffodil International University, Dhaka 1207, BangladeshDepartment of Pharmacy, Daffodil International University, Dhaka 1207, BangladeshDepartment of Pharmacy, Daffodil International University, Dhaka 1207, BangladeshDepartment of Radiological Sciences, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi ArabiaDepartment of Radiological Sciences, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi ArabiaDepartment of Radiological Sciences, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi ArabiaDepartment of Radiological Sciences, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi ArabiaCentre for Applied Physics and Radiation Technologies, School of Engineering and Technology, Sunway University, Bandar Sunway 47500, Selangor, MalaysiaDepartment of Chemistry, College of Science, King Khalid University, Abha 62529, Saudi ArabiaDepartment of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, BangladeshSeveral coronaviruses (CoVs) have been associated with serious health hazards in recent decades, resulting in the deaths of thousands around the globe. The recent coronavirus pandemic has emphasized the importance of discovering novel and effective antiviral medicines as quickly as possible to prevent more loss of human lives. Positive-sense RNA viruses with group spikes protruding from their surfaces and an abnormally large RNA genome enclose CoVs. CoVs have already been related to a range of respiratory infectious diseases possibly fatal to humans, such as MERS, SARS, and the current COVID-19 outbreak. As a result, effective prevention, treatment, and medications against human coronavirus (HCoV) is urgently needed. In recent years, many natural substances have been discovered with a variety of biological significance, including antiviral properties. Throughout this work, we reviewed a wide range of natural substances that interrupt the life cycles for MERS and SARS, as well as their potential application in the treatment of COVID-19.https://www.mdpi.com/1422-0067/22/23/12638bioactive moleculesalkaloidsflavonoidsterpenoidscoronavirusCOVID-19 |
| spellingShingle | Fahadul Islam Shabana Bibi Atkia Farzana Khan Meem Md. Mohaimenul Islam Md. Saidur Rahaman Sristy Bepary Md. Mizanur Rahman Md. Mominur Rahman Amin Elzaki Samih Kajoak Hamid Osman Mohamed ElSamani Mayeen Uddin Khandaker Abubakr M. Idris Talha Bin Emran Natural Bioactive Molecules: An Alternative Approach to the Treatment and Control of COVID-19 International Journal of Molecular Sciences bioactive molecules alkaloids flavonoids terpenoids coronavirus COVID-19 |
| title | Natural Bioactive Molecules: An Alternative Approach to the Treatment and Control of COVID-19 |
| title_full | Natural Bioactive Molecules: An Alternative Approach to the Treatment and Control of COVID-19 |
| title_fullStr | Natural Bioactive Molecules: An Alternative Approach to the Treatment and Control of COVID-19 |
| title_full_unstemmed | Natural Bioactive Molecules: An Alternative Approach to the Treatment and Control of COVID-19 |
| title_short | Natural Bioactive Molecules: An Alternative Approach to the Treatment and Control of COVID-19 |
| title_sort | natural bioactive molecules an alternative approach to the treatment and control of covid 19 |
| topic | bioactive molecules alkaloids flavonoids terpenoids coronavirus COVID-19 |
| url | https://www.mdpi.com/1422-0067/22/23/12638 |
| work_keys_str_mv | AT fahadulislam naturalbioactivemoleculesanalternativeapproachtothetreatmentandcontrolofcovid19 AT shabanabibi naturalbioactivemoleculesanalternativeapproachtothetreatmentandcontrolofcovid19 AT atkiafarzanakhanmeem naturalbioactivemoleculesanalternativeapproachtothetreatmentandcontrolofcovid19 AT mdmohaimenulislam naturalbioactivemoleculesanalternativeapproachtothetreatmentandcontrolofcovid19 AT mdsaidurrahaman naturalbioactivemoleculesanalternativeapproachtothetreatmentandcontrolofcovid19 AT sristybepary naturalbioactivemoleculesanalternativeapproachtothetreatmentandcontrolofcovid19 AT mdmizanurrahman naturalbioactivemoleculesanalternativeapproachtothetreatmentandcontrolofcovid19 AT mdmominurrahman naturalbioactivemoleculesanalternativeapproachtothetreatmentandcontrolofcovid19 AT aminelzaki naturalbioactivemoleculesanalternativeapproachtothetreatmentandcontrolofcovid19 AT samihkajoak naturalbioactivemoleculesanalternativeapproachtothetreatmentandcontrolofcovid19 AT hamidosman naturalbioactivemoleculesanalternativeapproachtothetreatmentandcontrolofcovid19 AT mohamedelsamani naturalbioactivemoleculesanalternativeapproachtothetreatmentandcontrolofcovid19 AT mayeenuddinkhandaker naturalbioactivemoleculesanalternativeapproachtothetreatmentandcontrolofcovid19 AT abubakrmidris naturalbioactivemoleculesanalternativeapproachtothetreatmentandcontrolofcovid19 AT talhabinemran naturalbioactivemoleculesanalternativeapproachtothetreatmentandcontrolofcovid19 |