Posttranscriptional control of the hypoxic response by RNA-binding proteins and microRNAs

Posttranscriptional control of the hypoxic response by RNA-binding proteins and microRNAs

Mammalian gene expression patterns change profoundly in response to low oxygen levels. These changes in gene expression programs are strongly influenced by post-transcriptional mechanisms mediated by mRNA-binding factors: RNA-binding proteins (RBPs) and microRNAs (miRNAs). Here, we review the RBPs...

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Bibliographic Details
Main Authors: Myriam eGorospe, Kumiko eTominaga, Xue eWu, Michael eFähling, Mircea eIvan
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
MicroRNAs
RNA-Binding Proteins
Untranslated Regions
hypoxia
translational control
mRNA turnover
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2011.00007/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2011.00007/full

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