Microvascular damage – a marker of specific organ involvement in mixed connective tissue disease?
Mixed connective tissue disease (MCTD) is a complex entity, which incorporates features of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis (SSc) and polymyositis/dermatomyositis (PM/DM). Nailfold videocapillaroscopy (NVC) is a simple, safe and non-invasive technique...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Termedia Publishing House
2021-04-01
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| Series: | Rheumatology |
| Subjects: | |
| Online Access: | https://www.termedia.pl/Microvascular-damage-a-marker-of-specific-organ-involvement-in-mixed-connective-tissue-disease-,18,43879,1,1.html |
| _version_ | 1818723224128585728 |
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| author | Sylwia Ornowska Marek Chojnowski Anna Felis-Giemza Łukasz Dudek Marzena Olesińska |
| author_facet | Sylwia Ornowska Marek Chojnowski Anna Felis-Giemza Łukasz Dudek Marzena Olesińska |
| author_sort | Sylwia Ornowska |
| collection | DOAJ |
| description | Mixed connective tissue disease (MCTD) is a complex entity, which incorporates features of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis (SSc) and polymyositis/dermatomyositis (PM/DM). Nailfold videocapillaroscopy (NVC) is a simple, safe and non-invasive technique of capillary vessel assessment, allowing for qualitative and quantitative assessment of microcirculation. NVC plays a pivotal role in the diagnostic algorithm of connective tissue diseases, especially in systemic sclerosis (SSc). Numerous studies have shown a correlation between organ involvement and disease progression in SSc.
In the current literature, there are limited data on relationship between NVC and organ involvement in MCTD patients. In the present article the relevant literature describing NVC examination in patients with MCTD and comparisons with some clinical situations are discussed. |
| first_indexed | 2024-12-17T21:07:07Z |
| format | Article |
| id | doaj.art-44288467ae4843d5bfd4ec60865cf45c |
| institution | Directory Open Access Journal |
| issn | 0034-6233 2084-9834 |
| language | English |
| last_indexed | 2024-12-17T21:07:07Z |
| publishDate | 2021-04-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Rheumatology |
| spelling | doaj.art-44288467ae4843d5bfd4ec60865cf45c2022-12-21T21:32:33ZengTermedia Publishing HouseRheumatology0034-62332084-98342021-04-0159211512010.5114/reum.2021.10545743879Microvascular damage – a marker of specific organ involvement in mixed connective tissue disease?Sylwia OrnowskaMarek ChojnowskiAnna Felis-GiemzaŁukasz DudekMarzena OlesińskaMixed connective tissue disease (MCTD) is a complex entity, which incorporates features of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis (SSc) and polymyositis/dermatomyositis (PM/DM). Nailfold videocapillaroscopy (NVC) is a simple, safe and non-invasive technique of capillary vessel assessment, allowing for qualitative and quantitative assessment of microcirculation. NVC plays a pivotal role in the diagnostic algorithm of connective tissue diseases, especially in systemic sclerosis (SSc). Numerous studies have shown a correlation between organ involvement and disease progression in SSc. In the current literature, there are limited data on relationship between NVC and organ involvement in MCTD patients. In the present article the relevant literature describing NVC examination in patients with MCTD and comparisons with some clinical situations are discussed.https://www.termedia.pl/Microvascular-damage-a-marker-of-specific-organ-involvement-in-mixed-connective-tissue-disease-,18,43879,1,1.htmlsystemic sclerosis connective tissue disease microscopy microvascular damage. |
| spellingShingle | Sylwia Ornowska Marek Chojnowski Anna Felis-Giemza Łukasz Dudek Marzena Olesińska Microvascular damage – a marker of specific organ involvement in mixed connective tissue disease? Rheumatology systemic sclerosis connective tissue disease microscopy microvascular damage. |
| title | Microvascular damage – a marker of specific organ involvement in mixed connective tissue disease? |
| title_full | Microvascular damage – a marker of specific organ involvement in mixed connective tissue disease? |
| title_fullStr | Microvascular damage – a marker of specific organ involvement in mixed connective tissue disease? |
| title_full_unstemmed | Microvascular damage – a marker of specific organ involvement in mixed connective tissue disease? |
| title_short | Microvascular damage – a marker of specific organ involvement in mixed connective tissue disease? |
| title_sort | microvascular damage a marker of specific organ involvement in mixed connective tissue disease |
| topic | systemic sclerosis connective tissue disease microscopy microvascular damage. |
| url | https://www.termedia.pl/Microvascular-damage-a-marker-of-specific-organ-involvement-in-mixed-connective-tissue-disease-,18,43879,1,1.html |
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