Electrochemotherapy for solid tumors: literature review and presentation of a novel endoscopic approach
Electrochemotherapy (ECT) is a minimally invasive and safe treatment gaining positive and long-lasting antitumoral results that are receiving the attention of the scientific community. It is a local treatment that combines the use of electroporation and the administration of cytotoxic drugs to induc...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2022-08-01
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Series: | Radiology and Oncology |
Subjects: | |
Online Access: | https://doi.org/10.2478/raon-2022-0022 |
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author | Schipilliti Francesca Matilde Onorato Maurizio Arrivi Giulia Panebianco Martina Lerinò Debora Milano Annalisa Roberto Michela Capalbo Carlo Mazzuca Federica |
author_facet | Schipilliti Francesca Matilde Onorato Maurizio Arrivi Giulia Panebianco Martina Lerinò Debora Milano Annalisa Roberto Michela Capalbo Carlo Mazzuca Federica |
author_sort | Schipilliti Francesca Matilde |
collection | DOAJ |
description | Electrochemotherapy (ECT) is a minimally invasive and safe treatment gaining positive and long-lasting antitumoral results that are receiving the attention of the scientific community. It is a local treatment that combines the use of electroporation and the administration of cytotoxic drugs to induce cell death in the target tissue. ECT is largely used for the treatment of cutaneous and subcutaneous lesions, and good results have been reported for the treatment of deep visceral tumors. The latest literature review is provided. Moreover, in line with its development for the treatment of visceral tumors in this article, we describe a novel approach of ECT: endoscopic treatment of colorectal cancer. Endoscopic ECT application was combined with systemic chemotherapy in the treatment of obstructing rectal cancer without prospective surgery. A good response after ECT was described: concentric involvement of the rectum was reduced, and no stenosing lesions were detected. |
first_indexed | 2024-04-09T18:29:38Z |
format | Article |
id | doaj.art-4428ab6bd7fb4243b9221080f8d0f0dd |
institution | Directory Open Access Journal |
issn | 1581-3207 |
language | English |
last_indexed | 2024-04-09T18:29:38Z |
publishDate | 2022-08-01 |
publisher | Sciendo |
record_format | Article |
series | Radiology and Oncology |
spelling | doaj.art-4428ab6bd7fb4243b9221080f8d0f0dd2023-04-11T17:19:28ZengSciendoRadiology and Oncology1581-32072022-08-0156328529110.2478/raon-2022-0022Electrochemotherapy for solid tumors: literature review and presentation of a novel endoscopic approachSchipilliti Francesca Matilde0Onorato MaurizioArrivi Giulia1Panebianco Martina2Lerinò Debora3Milano Annalisa4Roberto Michela5Capalbo Carlo6Mazzuca Federica7Oncological Department, Sant’Andrea Hospital, University Sapienza in Rome, Rome, ItalyOncological Department, Sant’Andrea Hospital, University Sapienza in Rome, Rome, ItalyOncological Department, Sant’Andrea Hospital, University Sapienza in Rome, Rome, ItalyOncological Department, Sant’Andrea Hospital, University Sapienza in Rome, Rome, ItalyOncological Department, Sant’Andrea Hospital, University Sapienza in Rome, Rome, ItalyOncological Department, University Sapienza in Rome, Rome, ItalyOncological Department, Sant’Andrea Hospital, University Sapienza in Rome, Rome, ItalyOncological Department, Sant’Andrea Hospital, University Sapienza in Rome, Rome, ItalyElectrochemotherapy (ECT) is a minimally invasive and safe treatment gaining positive and long-lasting antitumoral results that are receiving the attention of the scientific community. It is a local treatment that combines the use of electroporation and the administration of cytotoxic drugs to induce cell death in the target tissue. ECT is largely used for the treatment of cutaneous and subcutaneous lesions, and good results have been reported for the treatment of deep visceral tumors. The latest literature review is provided. Moreover, in line with its development for the treatment of visceral tumors in this article, we describe a novel approach of ECT: endoscopic treatment of colorectal cancer. Endoscopic ECT application was combined with systemic chemotherapy in the treatment of obstructing rectal cancer without prospective surgery. A good response after ECT was described: concentric involvement of the rectum was reduced, and no stenosing lesions were detected.https://doi.org/10.2478/raon-2022-0022electrochemotherapycolorectal cancerendoscopy |
spellingShingle | Schipilliti Francesca Matilde Onorato Maurizio Arrivi Giulia Panebianco Martina Lerinò Debora Milano Annalisa Roberto Michela Capalbo Carlo Mazzuca Federica Electrochemotherapy for solid tumors: literature review and presentation of a novel endoscopic approach Radiology and Oncology electrochemotherapy colorectal cancer endoscopy |
title | Electrochemotherapy for solid tumors: literature review and presentation of a novel endoscopic approach |
title_full | Electrochemotherapy for solid tumors: literature review and presentation of a novel endoscopic approach |
title_fullStr | Electrochemotherapy for solid tumors: literature review and presentation of a novel endoscopic approach |
title_full_unstemmed | Electrochemotherapy for solid tumors: literature review and presentation of a novel endoscopic approach |
title_short | Electrochemotherapy for solid tumors: literature review and presentation of a novel endoscopic approach |
title_sort | electrochemotherapy for solid tumors literature review and presentation of a novel endoscopic approach |
topic | electrochemotherapy colorectal cancer endoscopy |
url | https://doi.org/10.2478/raon-2022-0022 |
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