Patterns of tubercular lymphadenitis encountered in routine cytology reporting: An experience in a tertiary care center of Northeastern part of India
Background: Tuberculosis (TB) is the thirteenth leading cause of death and the second leading infectious killer after COVID-19 worldwide in 2020. Fine-needle aspiration (FNA) cytology is a simple and economic procedure for the diagnosis of TB at the initial stage. In this study, we tried to study th...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-01-01
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| Series: | MRIMS Journal of Health Sciences |
| Subjects: | |
| Online Access: | http://www.mrimsjournal.com/article.asp?issn=2321-7006;year=2024;volume=12;issue=1;spage=67;epage=70;aulast=Bhuyan |
| Summary: | Background: Tuberculosis (TB) is the thirteenth leading cause of death and the second leading infectious killer after COVID-19 worldwide in 2020. Fine-needle aspiration (FNA) cytology is a simple and economic procedure for the diagnosis of TB at the initial stage. In this study, we tried to study the various cytomorphological patterns of tubercular lymphadenitis encountered in routine practice.
Materials and Methods: This is a retrospective study that was carried out in a tertiary care setting in north eastern India between 2019 and 2022. We retrieved 305 cases of tubercular lymphadenitis and classified them into 4 morphological patterns. These were: pattern A-Epithelioid granuloma without necrosis; pattern B-Epithelioid granuloma with necrosis; pattern C-Necrosis without epithelioid granuloma and with numerous neutrophilic infiltrate; and pattern D-Cases with numerous macrophages.
Results: In our study, pattern C was the most common (44%) followed by pattern (23%); pattern B was seen in 80 cases (26%); and pattern D was seen in only 22 cases (7%). Among patients with HIV infection, the most common pattern was pattern D (80%).
Conclusion: This study shows that TB lymphadenitis is a disease with various morphological patterns. And understanding it can aid in the accurate diagnosis of tubercular lymphadenitis. |
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| ISSN: | 2321-7006 2321-7294 |