Effects of the administration of brewed Robusta coffee leaves on total antioxidant status in rats with high-fat, high-fructose diet-induced metabolic syndrome
Robusta coffee (Coffea canephora) leaves contain phytochemical compounds and have antioxidant and anti-diabetic effects. This study investigated the effect of brewed Robusta coffee leaves on the total antioxidant status in metabolic syndrome rats. Metabolic syndrome in rats was induced by high-fat-f...
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| Format: | Article |
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HACCP Consulting
2020-05-01
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| Series: | Potravinarstvo |
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| Online Access: | https://potravinarstvo.com/journal1/index.php/potravinarstvo/article/view/1350 |
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| author | Nurmasari Widyastuti Gemala Anjani Vita Gustin Almira Suci Eka Putri Amali Rica Pratiwi |
| author_facet | Nurmasari Widyastuti Gemala Anjani Vita Gustin Almira Suci Eka Putri Amali Rica Pratiwi |
| author_sort | Nurmasari Widyastuti |
| collection | DOAJ |
| description | Robusta coffee (Coffea canephora) leaves contain phytochemical compounds and have antioxidant and anti-diabetic effects. This study investigated the effect of brewed Robusta coffee leaves on the total antioxidant status in metabolic syndrome rats. Metabolic syndrome in rats was induced by high-fat-fructose diet containing pork oil (20%), cholesterol (1.5%), cholic acid (0.5%), standard feed (80%), and fructose (1 mL per 200 g BW). The animals were categorized into normal control group (K1), metabolic syndrome control group without treatment (K2), mangiferin treatment group (X1), brewed Robusta coffee leaves 0.09 g per 200 BW group (X2), brewed Robusta coffee leaves 0.18 g per 200 BW group (X3), and brewed Robusta coffee leaves 0.36 g per 200 BW group (X4). Each dose of the coffee leaves was brewed with 3.6 mL of water at 70 °C for 10 min. The intervention was administered for 28 days. There was a significant increase in the total antioxidant status (p <0.000) in all the groups. In conclusion, the administration of brewed Robusta coffee leaves increased the total antioxidant status in metabolic syndrome rats. |
| first_indexed | 2024-04-12T16:15:21Z |
| format | Article |
| id | doaj.art-442af40b516e43e991c0c6b389739a19 |
| institution | Directory Open Access Journal |
| issn | 1337-0960 |
| language | English |
| last_indexed | 2024-04-12T16:15:21Z |
| publishDate | 2020-05-01 |
| publisher | HACCP Consulting |
| record_format | Article |
| series | Potravinarstvo |
| spelling | doaj.art-442af40b516e43e991c0c6b389739a192022-12-22T03:25:44ZengHACCP ConsultingPotravinarstvo1337-09602020-05-011425826310.5219/1350983Effects of the administration of brewed Robusta coffee leaves on total antioxidant status in rats with high-fat, high-fructose diet-induced metabolic syndromeNurmasari Widyastuti0https://orcid.org/0000-0003-2964-2632Gemala Anjani1https://orcid.org/0000-0002-7774-7693Vita Gustin Almira2https://orcid.org/0000-0003-0432-9084Suci Eka Putri3Amali Rica Pratiwi4https://orcid.org/0000-0003-1293-2174Universitas Diponegoro, Faculty of Medicine, Department of Nutrition Science, Jl. Prof H. Soedarto, SH, Tembalang, 50275, Semarang, Indonesia, Tel.: +6281575897167,Universitas Diponegoro, Faculty of Medicine, Department of Nutrition Science, Jl. Prof H. Soedarto, SH, Tembalang, 50275, Semarang, Indonesia, Tel.: +6281285376785Universitas Diponegoro, Faculty of Medicine, Department of Nutrition Science, Jl. Prof H. Soedarto, SH, Tembalang, 50275, Semarang, Indonesia, Tel.: +62896702780780Universitas Diponegoro, Faculty of Medicine, Department of Nutrition Science, Jl. Prof H. Soedarto, SH, Tembalang, 50275, Semarang, Indonesia, Tel.: +6282391182648Universitas Diponegoro, Faculty of Medicine, Department of Nutrition Science, Jl. Prof H. Soedarto, SH, Tembalang, 50275, Semarang, Indonesia, Tel.: +6281232256199Robusta coffee (Coffea canephora) leaves contain phytochemical compounds and have antioxidant and anti-diabetic effects. This study investigated the effect of brewed Robusta coffee leaves on the total antioxidant status in metabolic syndrome rats. Metabolic syndrome in rats was induced by high-fat-fructose diet containing pork oil (20%), cholesterol (1.5%), cholic acid (0.5%), standard feed (80%), and fructose (1 mL per 200 g BW). The animals were categorized into normal control group (K1), metabolic syndrome control group without treatment (K2), mangiferin treatment group (X1), brewed Robusta coffee leaves 0.09 g per 200 BW group (X2), brewed Robusta coffee leaves 0.18 g per 200 BW group (X3), and brewed Robusta coffee leaves 0.36 g per 200 BW group (X4). Each dose of the coffee leaves was brewed with 3.6 mL of water at 70 °C for 10 min. The intervention was administered for 28 days. There was a significant increase in the total antioxidant status (p <0.000) in all the groups. In conclusion, the administration of brewed Robusta coffee leaves increased the total antioxidant status in metabolic syndrome rats.https://potravinarstvo.com/journal1/index.php/potravinarstvo/article/view/1350metabolic syndromerobusta coffee leavestotal antioxidant |
| spellingShingle | Nurmasari Widyastuti Gemala Anjani Vita Gustin Almira Suci Eka Putri Amali Rica Pratiwi Effects of the administration of brewed Robusta coffee leaves on total antioxidant status in rats with high-fat, high-fructose diet-induced metabolic syndrome Potravinarstvo metabolic syndrome robusta coffee leaves total antioxidant |
| title | Effects of the administration of brewed Robusta coffee leaves on total antioxidant status in rats with high-fat, high-fructose diet-induced metabolic syndrome |
| title_full | Effects of the administration of brewed Robusta coffee leaves on total antioxidant status in rats with high-fat, high-fructose diet-induced metabolic syndrome |
| title_fullStr | Effects of the administration of brewed Robusta coffee leaves on total antioxidant status in rats with high-fat, high-fructose diet-induced metabolic syndrome |
| title_full_unstemmed | Effects of the administration of brewed Robusta coffee leaves on total antioxidant status in rats with high-fat, high-fructose diet-induced metabolic syndrome |
| title_short | Effects of the administration of brewed Robusta coffee leaves on total antioxidant status in rats with high-fat, high-fructose diet-induced metabolic syndrome |
| title_sort | effects of the administration of brewed robusta coffee leaves on total antioxidant status in rats with high fat high fructose diet induced metabolic syndrome |
| topic | metabolic syndrome robusta coffee leaves total antioxidant |
| url | https://potravinarstvo.com/journal1/index.php/potravinarstvo/article/view/1350 |
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