A New Model to Investigate the Effects of Cosmetics on Skin Microorganisms In Vitro
The use of prebiotic substances in cosmetic products in order to improve skin appearance by influencing the skin microbiome has become quite common. As known from the food industry, prebiotic cosmetics aim for specific support of beneficial microorganisms, while others, especially pathogenic bacteri...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-08-01
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| Series: | Cosmetics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-9284/9/4/88 |
| _version_ | 1797410750926422016 |
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| author | Marian Rademacher Marc-Kevin Zinn Robert Beinio Dirk P. Bockmühl |
| author_facet | Marian Rademacher Marc-Kevin Zinn Robert Beinio Dirk P. Bockmühl |
| author_sort | Marian Rademacher |
| collection | DOAJ |
| description | The use of prebiotic substances in cosmetic products in order to improve skin appearance by influencing the skin microbiome has become quite common. As known from the food industry, prebiotic cosmetics aim for specific support of beneficial microorganisms, while others, especially pathogenic bacteria, are sought to be inhibited. To develop such products and evaluate their efficacy, it is crucial to understand the mode of action of prebiotic substances already before an in vivo use phase, e.g., by applying appropriate lab methods. We describe the development of a suitable in vitro model in order to test the efficacy of prebiotic substances incorporated in different types of formulas. A leather surface inoculated with different bacterial species of the human residential skin microbiota proved effective in simulating the action of prebiotic agents on the skin. It could be shown that the growth of bacteria was positively or negatively influenced by cosmetic formulas containing prebiotic substances. Thus, the model allows the investigation of prebiotic agents in cosmetic formulas with respect to their efficacy on a skin-like surface. |
| first_indexed | 2024-03-09T04:34:44Z |
| format | Article |
| id | doaj.art-442de9d34e234a2e95310cd5fbd84a71 |
| institution | Directory Open Access Journal |
| issn | 2079-9284 |
| language | English |
| last_indexed | 2024-03-09T04:34:44Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cosmetics |
| spelling | doaj.art-442de9d34e234a2e95310cd5fbd84a712023-12-03T13:29:36ZengMDPI AGCosmetics2079-92842022-08-01948810.3390/cosmetics9040088A New Model to Investigate the Effects of Cosmetics on Skin Microorganisms In VitroMarian Rademacher0Marc-Kevin Zinn1Robert Beinio2Dirk P. Bockmühl3Faculty of Life Sciences, Rhine-Waal University of Applied Sciences, 47533 Kleve, GermanyFaculty of Life Sciences, Rhine-Waal University of Applied Sciences, 47533 Kleve, Germanybb-med GmbH, 47546 Kalkar, GermanyFaculty of Life Sciences, Rhine-Waal University of Applied Sciences, 47533 Kleve, GermanyThe use of prebiotic substances in cosmetic products in order to improve skin appearance by influencing the skin microbiome has become quite common. As known from the food industry, prebiotic cosmetics aim for specific support of beneficial microorganisms, while others, especially pathogenic bacteria, are sought to be inhibited. To develop such products and evaluate their efficacy, it is crucial to understand the mode of action of prebiotic substances already before an in vivo use phase, e.g., by applying appropriate lab methods. We describe the development of a suitable in vitro model in order to test the efficacy of prebiotic substances incorporated in different types of formulas. A leather surface inoculated with different bacterial species of the human residential skin microbiota proved effective in simulating the action of prebiotic agents on the skin. It could be shown that the growth of bacteria was positively or negatively influenced by cosmetic formulas containing prebiotic substances. Thus, the model allows the investigation of prebiotic agents in cosmetic formulas with respect to their efficacy on a skin-like surface.https://www.mdpi.com/2079-9284/9/4/88skin microbiomemicrobiologyprebioticsskin modelclaim substantiationformulation |
| spellingShingle | Marian Rademacher Marc-Kevin Zinn Robert Beinio Dirk P. Bockmühl A New Model to Investigate the Effects of Cosmetics on Skin Microorganisms In Vitro Cosmetics skin microbiome microbiology prebiotics skin model claim substantiation formulation |
| title | A New Model to Investigate the Effects of Cosmetics on Skin Microorganisms In Vitro |
| title_full | A New Model to Investigate the Effects of Cosmetics on Skin Microorganisms In Vitro |
| title_fullStr | A New Model to Investigate the Effects of Cosmetics on Skin Microorganisms In Vitro |
| title_full_unstemmed | A New Model to Investigate the Effects of Cosmetics on Skin Microorganisms In Vitro |
| title_short | A New Model to Investigate the Effects of Cosmetics on Skin Microorganisms In Vitro |
| title_sort | new model to investigate the effects of cosmetics on skin microorganisms in vitro |
| topic | skin microbiome microbiology prebiotics skin model claim substantiation formulation |
| url | https://www.mdpi.com/2079-9284/9/4/88 |
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