Metastatic neuroendocrine tumors mimicking as primary ocular disease
Purpose: To report two cases of metastatic neuroendocrine tumors masquerading as primary ocular disease. Observations: Case 1 is a 38-year-old man who was referred with subacute onset diplopia and fluctuating ptosis suggestive of myasthenia gravis. Case 2 is a 21-year-old man who presented with blur...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-06-01
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| Series: | American Journal of Ophthalmology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451993622001712 |
| _version_ | 1828808109646151680 |
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| author | Alice Shen Arezu Haghighi Tom Liang On-Tat Lee William Gange Charles DeBoer Mashal Akhter Maria Sibug Saber Vivek R Patel Jesse L Berry Kimberly Kinga Gokoffski |
| author_facet | Alice Shen Arezu Haghighi Tom Liang On-Tat Lee William Gange Charles DeBoer Mashal Akhter Maria Sibug Saber Vivek R Patel Jesse L Berry Kimberly Kinga Gokoffski |
| author_sort | Alice Shen |
| collection | DOAJ |
| description | Purpose: To report two cases of metastatic neuroendocrine tumors masquerading as primary ocular disease. Observations: Case 1 is a 38-year-old man who was referred with subacute onset diplopia and fluctuating ptosis suggestive of myasthenia gravis. Case 2 is a 21-year-old man who presented with blurry vision and was found to have a pigmented ciliary body mass and retinal detachment suggestive of uveal melanoma. Both patients were ultimately diagnosed with metastatic neuroendocrine tumors. Conclusions and Importance: Neuroendocrine tumors, though rare and infrequently metastatic to the eye and orbit, can initially present with ocular signs. A broad differential and careful consideration of ocular and systemic symptoms are critical in such challenging cases. |
| first_indexed | 2024-12-12T08:35:50Z |
| format | Article |
| id | doaj.art-443405843b334e28b213867c641cd171 |
| institution | Directory Open Access Journal |
| issn | 2451-9936 |
| language | English |
| last_indexed | 2024-12-12T08:35:50Z |
| publishDate | 2022-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Ophthalmology Case Reports |
| spelling | doaj.art-443405843b334e28b213867c641cd1712022-12-22T00:30:56ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362022-06-0126101425Metastatic neuroendocrine tumors mimicking as primary ocular diseaseAlice Shen0Arezu Haghighi1Tom Liang2On-Tat Lee3William Gange4Charles DeBoer5Mashal Akhter6Maria Sibug Saber7Vivek R Patel8Jesse L Berry9Kimberly Kinga Gokoffski10Los Angeles County + University of Southern California Medical Center, Department of Ophthalmology, 2051 Marengo St, Los Angeles, CA, 90033, USALos Angeles County + University of Southern California Medical Center, Department of Ophthalmology, 2051 Marengo St, Los Angeles, CA, 90033, USALos Angeles County + University of Southern California Medical Center, Department of Ophthalmology, 2051 Marengo St, Los Angeles, CA, 90033, USALos Angeles County + University of Southern California Medical Center, Department of Ophthalmology, 2051 Marengo St, Los Angeles, CA, 90033, USALos Angeles County + University of Southern California Medical Center, Department of Ophthalmology, 2051 Marengo St, Los Angeles, CA, 90033, USALos Angeles County + University of Southern California Medical Center, Department of Ophthalmology, 2051 Marengo St, Los Angeles, CA, 90033, USALos Angeles County + University of Southern California Medical Center, Department of Ophthalmology, 2051 Marengo St, Los Angeles, CA, 90033, USALos Angeles County + University of Southern California Medical Center, Department of Ophthalmology, 2051 Marengo St, Los Angeles, CA, 90033, USALos Angeles County + University of Southern California Medical Center, Department of Ophthalmology, 2051 Marengo St, Los Angeles, CA, 90033, USALos Angeles County + University of Southern California Medical Center, Department of Ophthalmology, 2051 Marengo St, Los Angeles, CA, 90033, USACorresponding author. 1450 San Pablo St #4400, Los Angeles, CA, 90033.; Los Angeles County + University of Southern California Medical Center, Department of Ophthalmology, 2051 Marengo St, Los Angeles, CA, 90033, USAPurpose: To report two cases of metastatic neuroendocrine tumors masquerading as primary ocular disease. Observations: Case 1 is a 38-year-old man who was referred with subacute onset diplopia and fluctuating ptosis suggestive of myasthenia gravis. Case 2 is a 21-year-old man who presented with blurry vision and was found to have a pigmented ciliary body mass and retinal detachment suggestive of uveal melanoma. Both patients were ultimately diagnosed with metastatic neuroendocrine tumors. Conclusions and Importance: Neuroendocrine tumors, though rare and infrequently metastatic to the eye and orbit, can initially present with ocular signs. A broad differential and careful consideration of ocular and systemic symptoms are critical in such challenging cases.http://www.sciencedirect.com/science/article/pii/S2451993622001712Neuroendocrine tumorCiliary body tumorOrbital metastasisIntraocular metastasis |
| spellingShingle | Alice Shen Arezu Haghighi Tom Liang On-Tat Lee William Gange Charles DeBoer Mashal Akhter Maria Sibug Saber Vivek R Patel Jesse L Berry Kimberly Kinga Gokoffski Metastatic neuroendocrine tumors mimicking as primary ocular disease American Journal of Ophthalmology Case Reports Neuroendocrine tumor Ciliary body tumor Orbital metastasis Intraocular metastasis |
| title | Metastatic neuroendocrine tumors mimicking as primary ocular disease |
| title_full | Metastatic neuroendocrine tumors mimicking as primary ocular disease |
| title_fullStr | Metastatic neuroendocrine tumors mimicking as primary ocular disease |
| title_full_unstemmed | Metastatic neuroendocrine tumors mimicking as primary ocular disease |
| title_short | Metastatic neuroendocrine tumors mimicking as primary ocular disease |
| title_sort | metastatic neuroendocrine tumors mimicking as primary ocular disease |
| topic | Neuroendocrine tumor Ciliary body tumor Orbital metastasis Intraocular metastasis |
| url | http://www.sciencedirect.com/science/article/pii/S2451993622001712 |
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