DETECTION OF MUTATIONS RELATED TO HEREDITARY CANCER IN RELATIVES OF BREAST CANCER PATIENTS

DETECTION OF MUTATIONS RELATED TO HEREDITARY CANCER IN RELATIVES OF BREAST CANCER PATIENTS

The BRCA1 5382insC and CHEK2 1100 delC mutations were analyzed in 3850 of non-selected breast cancer patients residing in Novosibirsk region, Russia. One hundred seventy probands, BRCA1 5382insC or CHEK2 1100delC mutation carriers, were found. The study demonstrated that more than 80 % of probands i...

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Bibliographic Details
Main Authors:	G. A. Paul, N. A. Matyash, E. E. Pisareva, M. S. Anisimenko, A. E. Kozyakov, S. P. Kovalenko
Format:	Article
Language:	Russian
Published:	Russian Academy of Sciences, Tomsk National Research Medical Center 2017-09-01
Series:	Сибирский онкологический журнал
Subjects:	наследственный рак рак молочной железы молекулярно-генетический скрининг мутация brca1 5382insc мутация chek2 1100delc
Online Access:	https://www.siboncoj.ru/jour/article/view/573

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