Cas1 and Fen1 Display Equivalent Functions During Archaeal DNA Repair

Cas1 and Fen1 Display Equivalent Functions During Archaeal DNA Repair

CRISPR-Cas constitutes an adaptive prokaryotic defence system against invasive nucleic acids like viruses and plasmids. Beyond their role in immunity, CRISPR-Cas systems have been shown to closely interact with components of cellular DNA repair pathways, either by regulating their expression or via...

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Bibliographic Details
Main Authors: Julia Wörtz, Victoria Smith, Jörg Fallmann, Sabine König, Tharani Thuraisingam, Paul Walther, Henning Urlaub, Peter F. Stadler, Thorsten Allers, Frank Hille, Anita Marchfelder
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Microbiology
Subjects:
CRISPR-Cas
Cas1
DNA repair
Fen1
archaea
Haloferax volcanii
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.822304/full

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