Neurological Soft Signs: A Further Step in the Diagnosis of Bipolar-I Disorder?
Objectives: To study the prevalence and demographic characteristics of Neurological Soft Signs (NSS) among the patients with Bipolar Mood Disorder-I (BID). Method: In a cross- sectional descriptive-analytic study we studied 20 patients with BID with BID with 20 healthy individuals. We used DSM-IV a...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2009-03-01
|
| Series: | Iranian Journal of Psychiatry |
| Subjects: | |
| Online Access: | https://ijps.tums.ac.ir/index.php/ijps/article/view/491 |
| _version_ | 1818933209484754944 |
|---|---|
| author | Parastoo Irandoost Farhad Faridhosseini Homayoon Amini Maryam Noroozian Tajalli Saghaie |
| author_facet | Parastoo Irandoost Farhad Faridhosseini Homayoon Amini Maryam Noroozian Tajalli Saghaie |
| author_sort | Parastoo Irandoost |
| collection | DOAJ |
| description | Objectives: To study the prevalence and demographic characteristics of Neurological Soft Signs (NSS) among the patients with Bipolar Mood Disorder-I (BID).
Method: In a cross- sectional descriptive-analytic study we studied 20 patients with BID with BID with 20 healthy individuals. We used DSM-IV and Young Mania Rating Scale (MRS) for diagnosing and rating the patients with BID, Neurological Evaluation Scale along for assessment of NSS. Control subjects who were matched on age and sex were selected; other confounding factors such as age at the onset, severity and duration of the disease were also considered and analyzed to find any possible correlation with NSS.
Results: Total NSS scores were significantly higher in the patients' group (PV<0.0001). The most significant difference in NSS subscales was detected in the Sequencing of Complex Motor Acts (PV<0.0001). No significant correlation was found between NSS scores and age at the onset of the disease, severity and duration of the disease and medication.
Conclusion: This study may emphasize the role of NSS as a sign of organic brain disorder which may be present independent of medication effects in the patients with BID; however, further studies may be able to extend our findings to explore the etiology and pathogenesis of BID. |
| first_indexed | 2024-12-20T04:44:45Z |
| format | Article |
| id | doaj.art-443b0b1211774de7b2680dfc86c75ed1 |
| institution | Directory Open Access Journal |
| issn | 1735-4587 2008-2215 |
| language | English |
| last_indexed | 2024-12-20T04:44:45Z |
| publishDate | 2009-03-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Psychiatry |
| spelling | doaj.art-443b0b1211774de7b2680dfc86c75ed12022-12-21T19:53:01ZengTehran University of Medical SciencesIranian Journal of Psychiatry1735-45872008-22152009-03-0141Neurological Soft Signs: A Further Step in the Diagnosis of Bipolar-I Disorder?Parastoo Irandoost0Farhad Faridhosseini1Homayoon Amini2Maryam Noroozian3Tajalli Saghaie4Memory and Behavioral Neurology Department, Psychiatry and Psychology Research Center, Terhan University of Medical Sciences, IranBehavioral Sciences Research Center and Department of Psychiatry, Imam Hossein Hospital Shahid Beheshty University of Medical Sciences, IranMemory and Behavioral Neurology Department, Psychiatry and Psychology Research Center, Terhan University of Medical Sciences, IranMemory and Behavioral Neurology Department, Psychiatry and Psychology Research Center, Terhan University of Medical Sciences, IranMemory and Behavioral Neurology Department, Psychiatry and Psychology Research Center, Terhan University of Medical Sciences, IranObjectives: To study the prevalence and demographic characteristics of Neurological Soft Signs (NSS) among the patients with Bipolar Mood Disorder-I (BID). Method: In a cross- sectional descriptive-analytic study we studied 20 patients with BID with BID with 20 healthy individuals. We used DSM-IV and Young Mania Rating Scale (MRS) for diagnosing and rating the patients with BID, Neurological Evaluation Scale along for assessment of NSS. Control subjects who were matched on age and sex were selected; other confounding factors such as age at the onset, severity and duration of the disease were also considered and analyzed to find any possible correlation with NSS. Results: Total NSS scores were significantly higher in the patients' group (PV<0.0001). The most significant difference in NSS subscales was detected in the Sequencing of Complex Motor Acts (PV<0.0001). No significant correlation was found between NSS scores and age at the onset of the disease, severity and duration of the disease and medication. Conclusion: This study may emphasize the role of NSS as a sign of organic brain disorder which may be present independent of medication effects in the patients with BID; however, further studies may be able to extend our findings to explore the etiology and pathogenesis of BID.https://ijps.tums.ac.ir/index.php/ijps/article/view/491Bipolar- I DisorderNeurological Soft SignsNeurological examination |
| spellingShingle | Parastoo Irandoost Farhad Faridhosseini Homayoon Amini Maryam Noroozian Tajalli Saghaie Neurological Soft Signs: A Further Step in the Diagnosis of Bipolar-I Disorder? Iranian Journal of Psychiatry Bipolar- I Disorder Neurological Soft Signs Neurological examination |
| title | Neurological Soft Signs: A Further Step in the Diagnosis of Bipolar-I Disorder? |
| title_full | Neurological Soft Signs: A Further Step in the Diagnosis of Bipolar-I Disorder? |
| title_fullStr | Neurological Soft Signs: A Further Step in the Diagnosis of Bipolar-I Disorder? |
| title_full_unstemmed | Neurological Soft Signs: A Further Step in the Diagnosis of Bipolar-I Disorder? |
| title_short | Neurological Soft Signs: A Further Step in the Diagnosis of Bipolar-I Disorder? |
| title_sort | neurological soft signs a further step in the diagnosis of bipolar i disorder |
| topic | Bipolar- I Disorder Neurological Soft Signs Neurological examination |
| url | https://ijps.tums.ac.ir/index.php/ijps/article/view/491 |
| work_keys_str_mv | AT parastooirandoost neurologicalsoftsignsafurtherstepinthediagnosisofbipolaridisorder AT farhadfaridhosseini neurologicalsoftsignsafurtherstepinthediagnosisofbipolaridisorder AT homayoonamini neurologicalsoftsignsafurtherstepinthediagnosisofbipolaridisorder AT maryamnoroozian neurologicalsoftsignsafurtherstepinthediagnosisofbipolaridisorder AT tajallisaghaie neurologicalsoftsignsafurtherstepinthediagnosisofbipolaridisorder |