NLRP3 Inflammasome and Pyroptosis in Liver Pathophysiology: The Emerging Relevance of Nrf2 Inducers

NLRP3 Inflammasome and Pyroptosis in Liver Pathophysiology: The Emerging Relevance of Nrf2 Inducers

Inflammasomes, particularly the nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain containing 3 (NLRP3) inflammasome, apparently serve as crucial regulators of the inflammatory response through the activation of Caspase-1 and induction of pro-inflammatory cytokines and...

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Bibliographic Details
Main Authors: Laura Hurtado-Navarro, Diego Angosto-Bazarra, Pablo Pelegrín, Alberto Baroja-Mazo, Santiago Cuevas
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Antioxidants
Subjects:
liver diseases
fibrosis
NLRP3 inflammasome
pyoptosis
gasdermin
Nrf2
Online Access:https://www.mdpi.com/2076-3921/11/5/870

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