Dosing interval regimen shapes potency and breadth of antibody repertoire after vaccination of SARS-CoV-2 RBD protein subunit vaccine

Dosing interval regimen shapes potency and breadth of antibody repertoire after vaccination of SARS-CoV-2 RBD protein subunit vaccine

Abstract Vaccination with different vaccines has been implemented globally to counter the continuous COVID-19 pandemic. However, the vaccine-elicited antibodies have reduced efficiency against the highly mutated Omicron sub-variants. Previously, we developed a protein subunit COVID-19 vaccine called...

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Bibliographic Details
Main Authors: Shuxin Guo, Yuxuan Zheng, Zhengrong Gao, Minrun Duan, Sheng Liu, Pan Du, XiaoYu Xu, Kun Xu, Xin Zhao, Yan Chai, Peiyi Wang, Qi Zhao, George F. Gao, Lianpan Dai
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-023-00585-5

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