A single point mutation in the Listeria monocytogenes ribosomal gene rpsU enables SigB activation independently of the stressosome and the anti-sigma factor antagonist RsbV

A single point mutation in the Listeria monocytogenes ribosomal gene rpsU enables SigB activation independently of the stressosome and the anti-sigma factor antagonist RsbV

Microbial population heterogeneity leads to different stress responses and growth behavior of individual cells in a population. Previously, a point mutation in the rpsU gene (rpsUG50C) encoding ribosomal protein S21 was identified in a Listeria monocytogenes LO28 variant, which leads to increased mu...

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Bibliographic Details
Main Authors: Xuchuan Ma, Marcel H. Tempelaars, Marcel H. Zwietering, Sjef Boeren, Conor P. O’Byrne, Heidy M. W. den Besten, Tjakko Abee
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Microbiology
Subjects:
population heterogeneity
pathogen
variant
stress resistance
fitness
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1304325/full

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