Risk factors on surgical compliance and its impact on survival outcomes in meningioma patients: a SEER-based retrospective propensity-score matched analysis
Abstract Background This study aimed to analyze the effect of surgical compliance on the survival outcome of patients with meningioma and explore the factors affecting surgical compliance. Methods We selected data from the Surveillance, Epidemiology, and End Results database for 122,632 meningioma p...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | BMC Surgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12893-024-02326-1 |
| _version_ | 1797276052024721408 |
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| author | Shengkai Yang Hongwei Teng Yingdan Wang Kangkang Ji Weihua Chen Hai Zhou |
| author_facet | Shengkai Yang Hongwei Teng Yingdan Wang Kangkang Ji Weihua Chen Hai Zhou |
| author_sort | Shengkai Yang |
| collection | DOAJ |
| description | Abstract Background This study aimed to analyze the effect of surgical compliance on the survival outcome of patients with meningioma and explore the factors affecting surgical compliance. Methods We selected data from the Surveillance, Epidemiology, and End Results database for 122,632 meningioma patients diagnosed between 2004 and 2018. The effect of surgical compliance on patients’ overall survival (OS) was analyzed through Cox regression and Kaplan–Meier curves. Independent risk factors for surgical compliance were identified through multifactorial logistic regression analyses to construct diagnostic nomograms, further assessed by receiver operating characteristic curves. Furthermore, we used univariate and multivariate logistic regression analyses to evaluate relevant variables linked to adherence with meningioma surgery. Moreover, 1:1 propensity score matching was applied to assess the validity of the results in patients with favorable and poor surgical compliance. Results A total of 48,735 were eligible from the initial cohort of 122,632 patients with meningioma. Among them, 45,038 (92.40%) exhibited good surgical compliance, while 3697 (7.60%) had poor surgical compliance. The rate of patients with good surgical compliance was significantly higher than that of patients with inadequate surgical compliance (p < 0.001). Moreover, surgical compliance is an independent prognostic factor for OS in meningioma patients. Univariate Cox regression analysis indicated that individuals with poor surgical compliance demonstrated lower OS rates than those with good surgical compliance (hazard ratio [HR 2.404; 95% confidence interval [CI] 2.276–2.54, p < 0.001], consistent with the observation in the multivariate analysis (HR 1.564; 95% CI 1.471–1.663, p < 0.001). We developed a prediction model using seven variables: age, sex, race, tumor behavior recode, tumor size, family income, and residential setting (p < 0.05). Surgical compliance was associated with patient age, sex, race, tumor behavior recode, tumor size, family income, and residential setting by logistic regression analysis. Conclusions Surgical compliance emerged as an independent prognostic factor for survival in patients with meningioma. Poor surgical compliance was associated with older age, black and other races, females, advanced-stage tumors, larger tumor size, lower household income, and rural residence. When patients experienced these conditions, OS was shorter, requiring more aggressive treatment. |
| first_indexed | 2024-03-07T15:22:47Z |
| format | Article |
| id | doaj.art-4443b423da4843e18f5166fbce92e125 |
| institution | Directory Open Access Journal |
| issn | 1471-2482 |
| language | English |
| last_indexed | 2024-03-07T15:22:47Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Surgery |
| spelling | doaj.art-4443b423da4843e18f5166fbce92e1252024-03-05T17:31:03ZengBMCBMC Surgery1471-24822024-01-0124111510.1186/s12893-024-02326-1Risk factors on surgical compliance and its impact on survival outcomes in meningioma patients: a SEER-based retrospective propensity-score matched analysisShengkai Yang0Hongwei Teng1Yingdan Wang2Kangkang Ji3Weihua Chen4Hai Zhou5Department of Neurosurgery, Binhai County People’s HospitalDepartment of Neurosurgery, Binhai County People’s HospitalDepartment of Pediatric, Binhai County People’s HospitalDepartment of Central Laboratory, Binhai County People’s HospitalDepartment of Neurosurgery, Binhai County People’s HospitalDepartment of Neurosurgery, Binhai County People’s HospitalAbstract Background This study aimed to analyze the effect of surgical compliance on the survival outcome of patients with meningioma and explore the factors affecting surgical compliance. Methods We selected data from the Surveillance, Epidemiology, and End Results database for 122,632 meningioma patients diagnosed between 2004 and 2018. The effect of surgical compliance on patients’ overall survival (OS) was analyzed through Cox regression and Kaplan–Meier curves. Independent risk factors for surgical compliance were identified through multifactorial logistic regression analyses to construct diagnostic nomograms, further assessed by receiver operating characteristic curves. Furthermore, we used univariate and multivariate logistic regression analyses to evaluate relevant variables linked to adherence with meningioma surgery. Moreover, 1:1 propensity score matching was applied to assess the validity of the results in patients with favorable and poor surgical compliance. Results A total of 48,735 were eligible from the initial cohort of 122,632 patients with meningioma. Among them, 45,038 (92.40%) exhibited good surgical compliance, while 3697 (7.60%) had poor surgical compliance. The rate of patients with good surgical compliance was significantly higher than that of patients with inadequate surgical compliance (p < 0.001). Moreover, surgical compliance is an independent prognostic factor for OS in meningioma patients. Univariate Cox regression analysis indicated that individuals with poor surgical compliance demonstrated lower OS rates than those with good surgical compliance (hazard ratio [HR 2.404; 95% confidence interval [CI] 2.276–2.54, p < 0.001], consistent with the observation in the multivariate analysis (HR 1.564; 95% CI 1.471–1.663, p < 0.001). We developed a prediction model using seven variables: age, sex, race, tumor behavior recode, tumor size, family income, and residential setting (p < 0.05). Surgical compliance was associated with patient age, sex, race, tumor behavior recode, tumor size, family income, and residential setting by logistic regression analysis. Conclusions Surgical compliance emerged as an independent prognostic factor for survival in patients with meningioma. Poor surgical compliance was associated with older age, black and other races, females, advanced-stage tumors, larger tumor size, lower household income, and rural residence. When patients experienced these conditions, OS was shorter, requiring more aggressive treatment.https://doi.org/10.1186/s12893-024-02326-1MeningiomaSurgical complianceOverall survivalNomogramSEERPSM |
| spellingShingle | Shengkai Yang Hongwei Teng Yingdan Wang Kangkang Ji Weihua Chen Hai Zhou Risk factors on surgical compliance and its impact on survival outcomes in meningioma patients: a SEER-based retrospective propensity-score matched analysis BMC Surgery Meningioma Surgical compliance Overall survival Nomogram SEER PSM |
| title | Risk factors on surgical compliance and its impact on survival outcomes in meningioma patients: a SEER-based retrospective propensity-score matched analysis |
| title_full | Risk factors on surgical compliance and its impact on survival outcomes in meningioma patients: a SEER-based retrospective propensity-score matched analysis |
| title_fullStr | Risk factors on surgical compliance and its impact on survival outcomes in meningioma patients: a SEER-based retrospective propensity-score matched analysis |
| title_full_unstemmed | Risk factors on surgical compliance and its impact on survival outcomes in meningioma patients: a SEER-based retrospective propensity-score matched analysis |
| title_short | Risk factors on surgical compliance and its impact on survival outcomes in meningioma patients: a SEER-based retrospective propensity-score matched analysis |
| title_sort | risk factors on surgical compliance and its impact on survival outcomes in meningioma patients a seer based retrospective propensity score matched analysis |
| topic | Meningioma Surgical compliance Overall survival Nomogram SEER PSM |
| url | https://doi.org/10.1186/s12893-024-02326-1 |
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