Drug susceptibility of M. tuberculosis in tuberculosis patients from various population groups in Khanty-Mansiyskiy Autonomous Region
The study included 287 cultures of tuberculous mycobacteria received from specimens of patients from Khanty-Mansiysky TB Dispensary in 2011-2012. Patients from Khanty-Mansiysky TB Dispensary have a fairly high rate (24.0%) of co-infection of TB and HIV, especially among urban population (26.8%) comp...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2015-11-01
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| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/819 |
| _version_ | 1797759444797358080 |
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| author | Yu. V. Reshetnikova S. N. Аndreevskaya E. E. Larionova |
| author_facet | Yu. V. Reshetnikova S. N. Аndreevskaya E. E. Larionova |
| author_sort | Yu. V. Reshetnikova |
| collection | DOAJ |
| description | The study included 287 cultures of tuberculous mycobacteria received from specimens of patients from Khanty-Mansiysky TB Dispensary in 2011-2012. Patients from Khanty-Mansiysky TB Dispensary have a fairly high rate (24.0%) of co-infection of TB and HIV, especially among urban population (26.8%) compared to rural (13.6%) citizens. When analyzing the drug susceptibility of tuberculous mycobacteria isolated from pulmonary tuberculosis patients it has been found out that multiple drug resistant strains prevailed in the regions (56.8% of all drug resistant strains), and among them in more than a half of cases the strains were resistant not only to HR but to 3-4 additional TB drugs (29.3% of the total number of tested strains), which significantly increases the risk of treatment failure. |
| first_indexed | 2024-03-12T18:44:34Z |
| format | Article |
| id | doaj.art-4443c1ae23c549f794a0e9db05756f10 |
| institution | Directory Open Access Journal |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| last_indexed | 2024-03-12T18:44:34Z |
| publishDate | 2015-11-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj.art-4443c1ae23c549f794a0e9db05756f102023-08-02T07:47:50ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062015-11-010113640819Drug susceptibility of M. tuberculosis in tuberculosis patients from various population groups in Khanty-Mansiyskiy Autonomous RegionYu. V. Reshetnikova0S. N. Аndreevskaya1E. E. Larionova2КУ Ханты-Мансийского автономного округа - Югры «Ханты-Мансийский клинический противотуберкулезный диспансер»ФГБНУ «Центральный НИИ туберкулеза»ФГБНУ «Центральный НИИ туберкулеза»The study included 287 cultures of tuberculous mycobacteria received from specimens of patients from Khanty-Mansiysky TB Dispensary in 2011-2012. Patients from Khanty-Mansiysky TB Dispensary have a fairly high rate (24.0%) of co-infection of TB and HIV, especially among urban population (26.8%) compared to rural (13.6%) citizens. When analyzing the drug susceptibility of tuberculous mycobacteria isolated from pulmonary tuberculosis patients it has been found out that multiple drug resistant strains prevailed in the regions (56.8% of all drug resistant strains), and among them in more than a half of cases the strains were resistant not only to HR but to 3-4 additional TB drugs (29.3% of the total number of tested strains), which significantly increases the risk of treatment failure.https://www.tibl-journal.com/jour/article/view/819туберкулезмножественная лекарственная устойчивостьширокая лекарственная устойчивость |
| spellingShingle | Yu. V. Reshetnikova S. N. Аndreevskaya E. E. Larionova Drug susceptibility of M. tuberculosis in tuberculosis patients from various population groups in Khanty-Mansiyskiy Autonomous Region Туберкулез и болезни лёгких туберкулез множественная лекарственная устойчивость широкая лекарственная устойчивость |
| title | Drug susceptibility of M. tuberculosis in tuberculosis patients from various population groups in Khanty-Mansiyskiy Autonomous Region |
| title_full | Drug susceptibility of M. tuberculosis in tuberculosis patients from various population groups in Khanty-Mansiyskiy Autonomous Region |
| title_fullStr | Drug susceptibility of M. tuberculosis in tuberculosis patients from various population groups in Khanty-Mansiyskiy Autonomous Region |
| title_full_unstemmed | Drug susceptibility of M. tuberculosis in tuberculosis patients from various population groups in Khanty-Mansiyskiy Autonomous Region |
| title_short | Drug susceptibility of M. tuberculosis in tuberculosis patients from various population groups in Khanty-Mansiyskiy Autonomous Region |
| title_sort | drug susceptibility of m tuberculosis in tuberculosis patients from various population groups in khanty mansiyskiy autonomous region |
| topic | туберкулез множественная лекарственная устойчивость широкая лекарственная устойчивость |
| url | https://www.tibl-journal.com/jour/article/view/819 |
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