Longitudinal Plasmonic Detection of Glucose Using Gold Nanorods
Gold nanorod-based affinity sensors were developed utilizing concanavalin-A/dextran/glucose chemistry to detect glucose. The gold nanorods, synthesized using the seed-mediated method, were first coated with dextran sulfate. The dextran sulfate coating changed the local refractive index, which was ob...
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| Format: | Article |
| Language: | English |
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Wiley
2014-04-01
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| Series: | Nanomaterials and Nanotechnology |
| Subjects: | |
| Online Access: | http://www.intechopen.com/journals/nanomaterials_and_nanotechnology/longitudinal-plasmonic-detection-of-glucose-using-gold-nanorods |
| _version_ | 1826831854661009408 |
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| author | Ching-An Peng Sushil Pachpinde |
| author_facet | Ching-An Peng Sushil Pachpinde |
| author_sort | Ching-An Peng |
| collection | DOAJ |
| description | Gold nanorod-based affinity sensors were developed utilizing concanavalin-A/dextran/glucose chemistry to detect glucose. The gold nanorods, synthesized using the seed-mediated method, were first coated with dextran sulfate. The dextran sulfate coating changed the local refractive index, which was observed as a red shift in the longitudinal plasmon band. After the addition of 8 μM concanavalin-A, gold nanorod aggregates were formed as shown by TEM analysis. The corresponding UV-Vis spectrum peak wavelength showed a red shift from 701 nm of dextran sulfate coated gold nanorods to 718 nm of concanavalin-A promoted gold nanorod aggregates. The gold nanorod aggregates were dissociated when 12 mM glucose was introduced, as illustrated by TEM images. The longitudinal plasmon resonance of the UV-Vis spectrum also showed a blue shift from 718 nm of dextran sulfate-coated gold nanorods associated by concanavalin-A to 714 nm of dissociated dextran sulfate-coated gold nanorods. The degree of the spectrum peak wavelength shift of the dextran sulfate-coated gold nanorods associated by concanavalin-A can be modulated using glucose ranging from 1 to 30 mM. |
| first_indexed | 2024-03-09T09:03:01Z |
| format | Article |
| id | doaj.art-444b65850e20499cb45807c028e9c748 |
| institution | Directory Open Access Journal |
| issn | 1847-9804 |
| language | English |
| last_indexed | 2025-02-16T10:07:06Z |
| publishDate | 2014-04-01 |
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| series | Nanomaterials and Nanotechnology |
| spelling | doaj.art-444b65850e20499cb45807c028e9c7482025-02-03T01:29:37ZengWileyNanomaterials and Nanotechnology1847-98042014-04-0149http://dx.doi.org/10.5772/5853046468Longitudinal Plasmonic Detection of Glucose Using Gold NanorodsChing-An PengSushil PachpindeGold nanorod-based affinity sensors were developed utilizing concanavalin-A/dextran/glucose chemistry to detect glucose. The gold nanorods, synthesized using the seed-mediated method, were first coated with dextran sulfate. The dextran sulfate coating changed the local refractive index, which was observed as a red shift in the longitudinal plasmon band. After the addition of 8 μM concanavalin-A, gold nanorod aggregates were formed as shown by TEM analysis. The corresponding UV-Vis spectrum peak wavelength showed a red shift from 701 nm of dextran sulfate coated gold nanorods to 718 nm of concanavalin-A promoted gold nanorod aggregates. The gold nanorod aggregates were dissociated when 12 mM glucose was introduced, as illustrated by TEM images. The longitudinal plasmon resonance of the UV-Vis spectrum also showed a blue shift from 718 nm of dextran sulfate-coated gold nanorods associated by concanavalin-A to 714 nm of dissociated dextran sulfate-coated gold nanorods. The degree of the spectrum peak wavelength shift of the dextran sulfate-coated gold nanorods associated by concanavalin-A can be modulated using glucose ranging from 1 to 30 mM.http://www.intechopen.com/journals/nanomaterials_and_nanotechnology/longitudinal-plasmonic-detection-of-glucose-using-gold-nanorodsGold NanorodConcanavalin-ADextran SulfatePlasmon ResonanceGlucose |
| spellingShingle | Ching-An Peng Sushil Pachpinde Longitudinal Plasmonic Detection of Glucose Using Gold Nanorods Nanomaterials and Nanotechnology Gold Nanorod Concanavalin-A Dextran Sulfate Plasmon Resonance Glucose |
| title | Longitudinal Plasmonic Detection of Glucose Using Gold Nanorods |
| title_full | Longitudinal Plasmonic Detection of Glucose Using Gold Nanorods |
| title_fullStr | Longitudinal Plasmonic Detection of Glucose Using Gold Nanorods |
| title_full_unstemmed | Longitudinal Plasmonic Detection of Glucose Using Gold Nanorods |
| title_short | Longitudinal Plasmonic Detection of Glucose Using Gold Nanorods |
| title_sort | longitudinal plasmonic detection of glucose using gold nanorods |
| topic | Gold Nanorod Concanavalin-A Dextran Sulfate Plasmon Resonance Glucose |
| url | http://www.intechopen.com/journals/nanomaterials_and_nanotechnology/longitudinal-plasmonic-detection-of-glucose-using-gold-nanorods |
| work_keys_str_mv | AT chinganpeng longitudinalplasmonicdetectionofglucoseusinggoldnanorods AT sushilpachpinde longitudinalplasmonicdetectionofglucoseusinggoldnanorods |