IDIOPATHIC SICK SINUS SYNDROME

<p><strong>Aim.</strong> To evaluate changes in hereditary burden of sick sinus syndrome (SSS) in families of patients with SSS and assess heart rate variability (HRV) in patients with SSS.</p><p><strong>Results.</strong> 33 families of patients with SSS wer...

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Bibliographic Details
Main Authors: S. Y. Nikulina, V. A. Schulman, A. A. Chernova
Format: Article
Language:English
Published: Столичная издательская компания 2015-12-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:http://www.rpcardio.ru/jour/article/view/548
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Summary:<p><strong>Aim.</strong> To evaluate changes in hereditary burden of sick sinus syndrome (SSS) in families of patients with SSS and assess heart rate variability (HRV) in patients with SSS.</p><p><strong>Results.</strong> 33 families of patients with SSS were examined. Clinical study, ECG-Holter monitoring, atropine test, transesophageal left atrial stimulation, echocardiography, veloergometry were fulfilled in all probands and their relatives in 1990 and 2005-2006. Cardiorhythmography was done in patients with SSS only in 2005-2006.</p><p><strong>Results.</strong> Increase in hereditary burden with SSS from 31 to 35% is registered during 15 years. Significant growth of patients with SSS was observed among daughters (from 50 to 71%), nephews (from 33 to 50%) and nieces (from 0 to 20%). HRV analysis shows prevalence of sympathetic system activity in patients with SSS.</p><p><strong>Conclusion.</strong> Growth of hereditary burden with SSS especially among female relatives is shown. HRV analysis can be used for SSS diagnostics.</p>
ISSN:1819-6446
2225-3653