Rapidly separating dissolving microneedles with sustained-release colchicine and stabilized uricase for simplified long-term gout management

Rapidly separating dissolving microneedles with sustained-release colchicine and stabilized uricase for simplified long-term gout management

Despite growing prevalence and incidence, the management of gout remains suboptimal. The intermittent nature of the gout makes the long-term urate-lowering therapy (ULT) particularly important for gout management. However, patients are reluctant to take medication day after day to manage incurable o...

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Bibliographic Details
Main Authors: Yao Yang, Zimu Li, Ping Huang, Jiachan Lin, Jinyuan Li, Kexin Shi, Jiahui Lin, Jingwen Hu, Zhuoxian Zhao, Yongkang Yu, Hongzhong Chen, Xiaowei Zeng, Lin Mei
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Microneedles
Colchicine
Sustained-release
Uricase
Liposome
Transdermal administration
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383523000588

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