Overexpression of Dehydrogenase/Reductase 9 Predicts Poor Response to Concurrent Chemoradiotherapy and Poor Prognosis in Rectal Cancer Patients

Overexpression of Dehydrogenase/Reductase 9 Predicts Poor Response to Concurrent Chemoradiotherapy and Poor Prognosis in Rectal Cancer Patients

Objective: To reduce the risk of locoregional recurrence, the addition of neoadjuvant concurrent chemoradiotherapy (CCRT) is recommended before surgical management for rectal cancer patients. However, despite identical tumor histology, individual patient response to neoadjuvant CCRT varies greatly....

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Bibliographic Details
Main Authors: Tzu-Ju Chen, Bei-Hao Hsu, Sung-Wei Lee, Ching-Chieh Yang, Yu-Feng Tian, Yu-Hsuan Kuo, Wan-Shan Li, Hsin-Hwa Tsai, Li-Ching Wu, Cheng-Fa Yeh, Chia-Lin Chou, Hong-Yue Lai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Pathology and Oncology Research
Subjects:
biomarker
rectal cancer
DHRS9
epithelial cell differentiation
keratan sulfate
mucin
Online Access:https://www.por-journal.com/articles/10.3389/pore.2022.1610537/full

Internet

https://www.por-journal.com/articles/10.3389/pore.2022.1610537/full

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