Association between fat mass by bioelectrical impedance analysis and bone mass by quantitative ultrasound in relation to grip strength and serum 25-hydroxyvitamin D in postmenopausal Japanese women: the Unzen study
Abstract Background Whether fat mass or lean mass affects bone mass in postmenopausal women is controversial. This study aimed to explore the association between body composition measured by bioelectrical impedance analysis (BIA) and bone mass measured by quantitative ultrasound (QUS) in postmenopau...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-03-01
|
| Series: | Journal of Physiological Anthropology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40101-022-00281-5 |
| _version_ | 1818245580366807040 |
|---|---|
| author | Satoshi Mizukami Kazuhiko Arima Yasuyo Abe Yoshihito Tomita Hiroki Nakashima Yuzo Honda Michiko Uchiyama Tetsuji Ookawachi Hisashi Goto Maiko Hasegawa Youko Sou Mitsuo Kanagae Makoto Osaki Kiyoshi Aoyagi |
| author_facet | Satoshi Mizukami Kazuhiko Arima Yasuyo Abe Yoshihito Tomita Hiroki Nakashima Yuzo Honda Michiko Uchiyama Tetsuji Ookawachi Hisashi Goto Maiko Hasegawa Youko Sou Mitsuo Kanagae Makoto Osaki Kiyoshi Aoyagi |
| author_sort | Satoshi Mizukami |
| collection | DOAJ |
| description | Abstract Background Whether fat mass or lean mass affects bone mass in postmenopausal women is controversial. This study aimed to explore the association between body composition measured by bioelectrical impedance analysis (BIA) and bone mass measured by quantitative ultrasound (QUS) in postmenopausal women in Japan. Methods We conducted a cross-sectional study, The Unzen Study, on 382 community-dwelling postmenopausal Japanese women (mean (standard deviation) age: 68.2 (7.2) years) who participated in periodic health examinations. The stiffness index (SI) was measured using QUS, and body composition (e.g., fat mass and muscle mass) was measured using BIA. Grip strength was measured. Fasting blood samples were collected, and 25-hydroxyvitamin D (25(OH)D), tartrate-resistant acid phosphatase-5b (TRACP-5b), and parathyroid hormone (PTH) levels were measured. Data on current smoking, alcohol consumption, exercise, and any comorbidities (heart disease, lung disease, stroke, or diabetes mellitus) were collected. Results The SI increased with increasing quartiles of fat mass and muscle mass (both p for trend < 0.001), respectively. There were positive correlations between SI and log (25(OH)D) or grip strength. Fat mass significantly correlated with grip strength. Multiple linear regression analysis showed that higher fat mass was independently and significantly associated with higher SI after adjusting for age, height, comorbidity, current smoking, alcohol consumption, exercise, log (25(OH)D), log (TRACP-5b), log (PTH), and grip strength (p = 0.001). In contrast, no association was observed between muscle mass and SI. Conclusions Fat mass, but not muscle mass, was a significant determinant of SI in community-dwelling postmenopausal Japanese women. |
| first_indexed | 2024-12-12T14:35:10Z |
| format | Article |
| id | doaj.art-4457d0fbb7124445a6554b6bcaed155a |
| institution | Directory Open Access Journal |
| issn | 1880-6805 |
| language | English |
| last_indexed | 2024-12-12T14:35:10Z |
| publishDate | 2022-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Physiological Anthropology |
| spelling | doaj.art-4457d0fbb7124445a6554b6bcaed155a2022-12-22T00:21:23ZengBMCJournal of Physiological Anthropology1880-68052022-03-014111810.1186/s40101-022-00281-5Association between fat mass by bioelectrical impedance analysis and bone mass by quantitative ultrasound in relation to grip strength and serum 25-hydroxyvitamin D in postmenopausal Japanese women: the Unzen studySatoshi Mizukami0Kazuhiko Arima1Yasuyo Abe2Yoshihito Tomita3Hiroki Nakashima4Yuzo Honda5Michiko Uchiyama6Tetsuji Ookawachi7Hisashi Goto8Maiko Hasegawa9Youko Sou10Mitsuo Kanagae11Makoto Osaki12Kiyoshi Aoyagi13Department of Public Health, Nagasaki University Graduate School of Biomedical SciencesDepartment of Public Health, Nagasaki University Graduate School of Biomedical SciencesDepartment of Health and Nutrition Science, Nishikyusyu UniversityDepartment of Public Health, Nagasaki University Graduate School of Biomedical SciencesDepartment of Public Health, Nagasaki University Graduate School of Biomedical SciencesDepartment of Public Health, Nagasaki University Graduate School of Biomedical SciencesDepartment of Public Health, Nagasaki University Graduate School of Biomedical SciencesDepartment of Public Health, Nagasaki University Graduate School of Biomedical SciencesKen-Hoku Health Care OfficeMedical Policy Division, Nagasaki Prefectural GovernmentNational Health Insurance & Health Improvement Division, Nagasaki Prefectural GovernmentDepartment of Public Health, Nagasaki University Graduate School of Biomedical SciencesDepartment of Orthopedic Surgery, Nagasaki University Graduate School of Biomedical SciencesDepartment of Public Health, Nagasaki University Graduate School of Biomedical SciencesAbstract Background Whether fat mass or lean mass affects bone mass in postmenopausal women is controversial. This study aimed to explore the association between body composition measured by bioelectrical impedance analysis (BIA) and bone mass measured by quantitative ultrasound (QUS) in postmenopausal women in Japan. Methods We conducted a cross-sectional study, The Unzen Study, on 382 community-dwelling postmenopausal Japanese women (mean (standard deviation) age: 68.2 (7.2) years) who participated in periodic health examinations. The stiffness index (SI) was measured using QUS, and body composition (e.g., fat mass and muscle mass) was measured using BIA. Grip strength was measured. Fasting blood samples were collected, and 25-hydroxyvitamin D (25(OH)D), tartrate-resistant acid phosphatase-5b (TRACP-5b), and parathyroid hormone (PTH) levels were measured. Data on current smoking, alcohol consumption, exercise, and any comorbidities (heart disease, lung disease, stroke, or diabetes mellitus) were collected. Results The SI increased with increasing quartiles of fat mass and muscle mass (both p for trend < 0.001), respectively. There were positive correlations between SI and log (25(OH)D) or grip strength. Fat mass significantly correlated with grip strength. Multiple linear regression analysis showed that higher fat mass was independently and significantly associated with higher SI after adjusting for age, height, comorbidity, current smoking, alcohol consumption, exercise, log (25(OH)D), log (TRACP-5b), log (PTH), and grip strength (p = 0.001). In contrast, no association was observed between muscle mass and SI. Conclusions Fat mass, but not muscle mass, was a significant determinant of SI in community-dwelling postmenopausal Japanese women.https://doi.org/10.1186/s40101-022-00281-5Body compositionFat massMuscle massBone massStiffness indexPostmenopausal women |
| spellingShingle | Satoshi Mizukami Kazuhiko Arima Yasuyo Abe Yoshihito Tomita Hiroki Nakashima Yuzo Honda Michiko Uchiyama Tetsuji Ookawachi Hisashi Goto Maiko Hasegawa Youko Sou Mitsuo Kanagae Makoto Osaki Kiyoshi Aoyagi Association between fat mass by bioelectrical impedance analysis and bone mass by quantitative ultrasound in relation to grip strength and serum 25-hydroxyvitamin D in postmenopausal Japanese women: the Unzen study Journal of Physiological Anthropology Body composition Fat mass Muscle mass Bone mass Stiffness index Postmenopausal women |
| title | Association between fat mass by bioelectrical impedance analysis and bone mass by quantitative ultrasound in relation to grip strength and serum 25-hydroxyvitamin D in postmenopausal Japanese women: the Unzen study |
| title_full | Association between fat mass by bioelectrical impedance analysis and bone mass by quantitative ultrasound in relation to grip strength and serum 25-hydroxyvitamin D in postmenopausal Japanese women: the Unzen study |
| title_fullStr | Association between fat mass by bioelectrical impedance analysis and bone mass by quantitative ultrasound in relation to grip strength and serum 25-hydroxyvitamin D in postmenopausal Japanese women: the Unzen study |
| title_full_unstemmed | Association between fat mass by bioelectrical impedance analysis and bone mass by quantitative ultrasound in relation to grip strength and serum 25-hydroxyvitamin D in postmenopausal Japanese women: the Unzen study |
| title_short | Association between fat mass by bioelectrical impedance analysis and bone mass by quantitative ultrasound in relation to grip strength and serum 25-hydroxyvitamin D in postmenopausal Japanese women: the Unzen study |
| title_sort | association between fat mass by bioelectrical impedance analysis and bone mass by quantitative ultrasound in relation to grip strength and serum 25 hydroxyvitamin d in postmenopausal japanese women the unzen study |
| topic | Body composition Fat mass Muscle mass Bone mass Stiffness index Postmenopausal women |
| url | https://doi.org/10.1186/s40101-022-00281-5 |
| work_keys_str_mv | AT satoshimizukami associationbetweenfatmassbybioelectricalimpedanceanalysisandbonemassbyquantitativeultrasoundinrelationtogripstrengthandserum25hydroxyvitamindinpostmenopausaljapanesewomentheunzenstudy AT kazuhikoarima associationbetweenfatmassbybioelectricalimpedanceanalysisandbonemassbyquantitativeultrasoundinrelationtogripstrengthandserum25hydroxyvitamindinpostmenopausaljapanesewomentheunzenstudy AT yasuyoabe associationbetweenfatmassbybioelectricalimpedanceanalysisandbonemassbyquantitativeultrasoundinrelationtogripstrengthandserum25hydroxyvitamindinpostmenopausaljapanesewomentheunzenstudy AT yoshihitotomita associationbetweenfatmassbybioelectricalimpedanceanalysisandbonemassbyquantitativeultrasoundinrelationtogripstrengthandserum25hydroxyvitamindinpostmenopausaljapanesewomentheunzenstudy AT hirokinakashima associationbetweenfatmassbybioelectricalimpedanceanalysisandbonemassbyquantitativeultrasoundinrelationtogripstrengthandserum25hydroxyvitamindinpostmenopausaljapanesewomentheunzenstudy AT yuzohonda associationbetweenfatmassbybioelectricalimpedanceanalysisandbonemassbyquantitativeultrasoundinrelationtogripstrengthandserum25hydroxyvitamindinpostmenopausaljapanesewomentheunzenstudy AT michikouchiyama associationbetweenfatmassbybioelectricalimpedanceanalysisandbonemassbyquantitativeultrasoundinrelationtogripstrengthandserum25hydroxyvitamindinpostmenopausaljapanesewomentheunzenstudy AT tetsujiookawachi associationbetweenfatmassbybioelectricalimpedanceanalysisandbonemassbyquantitativeultrasoundinrelationtogripstrengthandserum25hydroxyvitamindinpostmenopausaljapanesewomentheunzenstudy AT hisashigoto associationbetweenfatmassbybioelectricalimpedanceanalysisandbonemassbyquantitativeultrasoundinrelationtogripstrengthandserum25hydroxyvitamindinpostmenopausaljapanesewomentheunzenstudy AT maikohasegawa associationbetweenfatmassbybioelectricalimpedanceanalysisandbonemassbyquantitativeultrasoundinrelationtogripstrengthandserum25hydroxyvitamindinpostmenopausaljapanesewomentheunzenstudy AT youkosou associationbetweenfatmassbybioelectricalimpedanceanalysisandbonemassbyquantitativeultrasoundinrelationtogripstrengthandserum25hydroxyvitamindinpostmenopausaljapanesewomentheunzenstudy AT mitsuokanagae associationbetweenfatmassbybioelectricalimpedanceanalysisandbonemassbyquantitativeultrasoundinrelationtogripstrengthandserum25hydroxyvitamindinpostmenopausaljapanesewomentheunzenstudy AT makotoosaki associationbetweenfatmassbybioelectricalimpedanceanalysisandbonemassbyquantitativeultrasoundinrelationtogripstrengthandserum25hydroxyvitamindinpostmenopausaljapanesewomentheunzenstudy AT kiyoshiaoyagi associationbetweenfatmassbybioelectricalimpedanceanalysisandbonemassbyquantitativeultrasoundinrelationtogripstrengthandserum25hydroxyvitamindinpostmenopausaljapanesewomentheunzenstudy |