Adenosine, bridging chronic inflammation and tumor growth

Adenosine, bridging chronic inflammation and tumor growth

Adenosine (Ado) is a well-known immunosuppressive agent that may be released or generated extracellularly by cells, via degrading ATP by the sequential actions of the ectonucleotides CD39 and CD73. During inflammation Ado is produced by leukocytes and tissue cells by different means to initiate the...

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Bibliographic Details
Main Authors: Luxia Chen, Mohamad Alabdullah, Karsten Mahnke
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
adenosine
tumor
chronic inflammation
immunosuppression
hypoxia
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1258637/full

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