MethScore as a new comprehensive DNA methylation-based value refining the prognosis in acute myeloid leukemia

Abstract Background Changes in DNA methylation are common events in the pathogenesis of acute myeloid leukemia (AML) and have been repeatedly reported as associated with prognosis. However, studies integrating these numerous and potentially prognostically relevant DNA methylation changes are lacking...

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Main Authors: Šárka Šestáková, Cyril Šálek, Dávid Kundrát, Ela Cerovská, Jan Vydra, Ivana Ježíšková, Adam Folta, Jiří Mayer, Petr Cetkovský, Hana Remešová
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Clinical Epigenetics
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Online Access:https://doi.org/10.1186/s13148-024-01625-x