Direct Immunofluorescence of Skin and Oral Mucosa: Guidelines for Selecting the Optimum Biopsy Site
Direct immunofluorescence is a vital diagnostic test for assessing vesiculobullous disorders, vasculitides, and connective tissue diseases. It is a robust and valuable technique that offers essential diagnostic information for many critical dermatoses. Dermatopathologists depend heavily on the data...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Dermatopathology |
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| Online Access: | https://www.mdpi.com/2296-3529/11/1/6 |
| _version_ | 1797241438889574400 |
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| author | Muhammad N. Mahmood |
| author_facet | Muhammad N. Mahmood |
| author_sort | Muhammad N. Mahmood |
| collection | DOAJ |
| description | Direct immunofluorescence is a vital diagnostic test for assessing vesiculobullous disorders, vasculitides, and connective tissue diseases. It is a robust and valuable technique that offers essential diagnostic information for many critical dermatoses. Dermatopathologists depend heavily on the data obtained from direct immunofluorescence evaluation to confirm final diagnoses. Selecting the most appropriate biopsy site is necessary for maximizing diagnostic accuracy, and the best site may vary depending on the clinical differential diagnosis. Inaccurate biopsy site selection can significantly impact the accuracy of the results. To optimize the use of direct immunofluorescence studies, this review provides helpful guidelines and some practical tips for selecting the best biopsy site. |
| first_indexed | 2024-04-24T18:23:20Z |
| format | Article |
| id | doaj.art-445a3881124b461cbb1dae715171b092 |
| institution | Directory Open Access Journal |
| issn | 2296-3529 |
| language | English |
| last_indexed | 2024-04-24T18:23:20Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Dermatopathology |
| spelling | doaj.art-445a3881124b461cbb1dae715171b0922024-03-27T13:33:06ZengMDPI AGDermatopathology2296-35292024-01-01111526110.3390/dermatopathology11010006Direct Immunofluorescence of Skin and Oral Mucosa: Guidelines for Selecting the Optimum Biopsy SiteMuhammad N. Mahmood0Department of Laboratory Medicine and Pathology, University of Alberta Hospital, Edmonton, AB T6G 2B7, CanadaDirect immunofluorescence is a vital diagnostic test for assessing vesiculobullous disorders, vasculitides, and connective tissue diseases. It is a robust and valuable technique that offers essential diagnostic information for many critical dermatoses. Dermatopathologists depend heavily on the data obtained from direct immunofluorescence evaluation to confirm final diagnoses. Selecting the most appropriate biopsy site is necessary for maximizing diagnostic accuracy, and the best site may vary depending on the clinical differential diagnosis. Inaccurate biopsy site selection can significantly impact the accuracy of the results. To optimize the use of direct immunofluorescence studies, this review provides helpful guidelines and some practical tips for selecting the best biopsy site.https://www.mdpi.com/2296-3529/11/1/6direct immunofluorescencebiopsy sitevesiculobullous disordervasculitisconnective tissue diseaseoral mucosa |
| spellingShingle | Muhammad N. Mahmood Direct Immunofluorescence of Skin and Oral Mucosa: Guidelines for Selecting the Optimum Biopsy Site Dermatopathology direct immunofluorescence biopsy site vesiculobullous disorder vasculitis connective tissue disease oral mucosa |
| title | Direct Immunofluorescence of Skin and Oral Mucosa: Guidelines for Selecting the Optimum Biopsy Site |
| title_full | Direct Immunofluorescence of Skin and Oral Mucosa: Guidelines for Selecting the Optimum Biopsy Site |
| title_fullStr | Direct Immunofluorescence of Skin and Oral Mucosa: Guidelines for Selecting the Optimum Biopsy Site |
| title_full_unstemmed | Direct Immunofluorescence of Skin and Oral Mucosa: Guidelines for Selecting the Optimum Biopsy Site |
| title_short | Direct Immunofluorescence of Skin and Oral Mucosa: Guidelines for Selecting the Optimum Biopsy Site |
| title_sort | direct immunofluorescence of skin and oral mucosa guidelines for selecting the optimum biopsy site |
| topic | direct immunofluorescence biopsy site vesiculobullous disorder vasculitis connective tissue disease oral mucosa |
| url | https://www.mdpi.com/2296-3529/11/1/6 |
| work_keys_str_mv | AT muhammadnmahmood directimmunofluorescenceofskinandoralmucosaguidelinesforselectingtheoptimumbiopsysite |