DIFFERENTIAL APPROACH TO ADENOMYOSIS TREATMENT

This article presents results of authors' own investigations using a new approach to treatment of adenomyosis (uterine endometriotic lesions which are most often found within the structure of genital endometriosis) and differential characteristics of different (by their activity) forms of disea...

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Main Authors: I. S. Sidorova, A. L. Unanyan
Format: Article
Language:Russian
Published: IRBIS LLC 2016-09-01
Series:Акушерство, гинекология и репродукция
Subjects:
Online Access:https://www.gynecology.su/jour/article/view/270
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author I. S. Sidorova
A. L. Unanyan
author_facet I. S. Sidorova
A. L. Unanyan
author_sort I. S. Sidorova
collection DOAJ
description This article presents results of authors' own investigations using a new approach to treatment of adenomyosis (uterine endometriotic lesions which are most often found within the structure of genital endometriosis) and differential characteristics of different (by their activity) forms of disease. The investigation included 492 female patients. Depending on the intensity of main clinical manifestations characteristic for adenomyosis, the examined females were divided into 2 groups: the 1st group comprised 344 patients with clinically active adenomyosis, and the second group included 148 patients with clinically inactive adenomyosis. 321 (65.2%) out of 492 (100%) adenomyosis patients were subjected to separate therapeutic and diagnostic endocervical and uterine cavity curettage followed by hysterectomy. 171 (34.8%) of females have received a course of conservative treatment (in 114 patients of the total - after separate diagnostic curettage). 113 adenomyosis patients (64 from group I and 49 from group II - without hysterectomy) have received a 6-month course of treatment by GnRh-A (gonadotropin-releasing hormone agonists) with pronounced positive effect. After completion of the GnRh-A course, a complex treatment was used with monophasic combination oral contraceptives (OC) in the extended regimen. This approach is highly efficacious and to a large extent enables to put into effect the organ-saving tactics of adenomyosis treatment which is particularly important in the reproductive age.
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spelling doaj.art-445b7609cf094c17b0d6922437af9b582023-03-13T07:09:48ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942016-09-01521620268DIFFERENTIAL APPROACH TO ADENOMYOSIS TREATMENTI. S. Sidorova0A. L. Unanyan1I.M. Sechenov Moscow State Medical University (MSMU), MoscowI.M. Sechenov Moscow State Medical University (MSMU), MoscowThis article presents results of authors' own investigations using a new approach to treatment of adenomyosis (uterine endometriotic lesions which are most often found within the structure of genital endometriosis) and differential characteristics of different (by their activity) forms of disease. The investigation included 492 female patients. Depending on the intensity of main clinical manifestations characteristic for adenomyosis, the examined females were divided into 2 groups: the 1st group comprised 344 patients with clinically active adenomyosis, and the second group included 148 patients with clinically inactive adenomyosis. 321 (65.2%) out of 492 (100%) adenomyosis patients were subjected to separate therapeutic and diagnostic endocervical and uterine cavity curettage followed by hysterectomy. 171 (34.8%) of females have received a course of conservative treatment (in 114 patients of the total - after separate diagnostic curettage). 113 adenomyosis patients (64 from group I and 49 from group II - without hysterectomy) have received a 6-month course of treatment by GnRh-A (gonadotropin-releasing hormone agonists) with pronounced positive effect. After completion of the GnRh-A course, a complex treatment was used with monophasic combination oral contraceptives (OC) in the extended regimen. This approach is highly efficacious and to a large extent enables to put into effect the organ-saving tactics of adenomyosis treatment which is particularly important in the reproductive age.https://www.gynecology.su/jour/article/view/270adenomyosisgonadotropin-releasing hormone agonistscombination oral contraceptives
spellingShingle I. S. Sidorova
A. L. Unanyan
DIFFERENTIAL APPROACH TO ADENOMYOSIS TREATMENT
Акушерство, гинекология и репродукция
adenomyosis
gonadotropin-releasing hormone agonists
combination oral contraceptives
title DIFFERENTIAL APPROACH TO ADENOMYOSIS TREATMENT
title_full DIFFERENTIAL APPROACH TO ADENOMYOSIS TREATMENT
title_fullStr DIFFERENTIAL APPROACH TO ADENOMYOSIS TREATMENT
title_full_unstemmed DIFFERENTIAL APPROACH TO ADENOMYOSIS TREATMENT
title_short DIFFERENTIAL APPROACH TO ADENOMYOSIS TREATMENT
title_sort differential approach to adenomyosis treatment
topic adenomyosis
gonadotropin-releasing hormone agonists
combination oral contraceptives
url https://www.gynecology.su/jour/article/view/270
work_keys_str_mv AT issidorova differentialapproachtoadenomyosistreatment
AT alunanyan differentialapproachtoadenomyosistreatment