The potential of the use of antitude therapy in pediatric practice
Introduction.Coughing affects quality of life and is the most common reason patients seek medical attention. In children, establishing the pathophysiological cause of the condition associated with cough is of particular importance for making an adequate diagnosis and prescribing the correct therapy....
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| Format: | Article |
| Language: | Russian |
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Remedium Group LLC
2020-11-01
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| Series: | Медицинский совет |
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| Online Access: | https://www.med-sovet.pro/jour/article/view/5895 |
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| author | E. L. Rashitova A. M. Zakirova T. B. Moroz D. T. Shayapova A. G. Kadriev A. A. Kadriev |
| author_facet | E. L. Rashitova A. M. Zakirova T. B. Moroz D. T. Shayapova A. G. Kadriev A. A. Kadriev |
| author_sort | E. L. Rashitova |
| collection | DOAJ |
| description | Introduction.Coughing affects quality of life and is the most common reason patients seek medical attention. In children, establishing the pathophysiological cause of the condition associated with cough is of particular importance for making an adequate diagnosis and prescribing the correct therapy.Target. To assess the efficacy and safety of butamirate use in the complex treatment of preschoolers with acute bronchitis.Materials and methods. The initiative study was carried out in accordance with the requirements of the Declaration of Helsinki and included 63 patients with a dry cough symptom at the age of 3–7 years with a diagnosis of acute bronchitis. The effectiveness of therapy was assessed using a point system. In the main (1) group – 21 children – used a non-narcotic antitussive drug of central action butamirate, 5 ml of syrup 3 times/day before meals for 4,7 ± 0,6 days. In the main (2) group – 21 children – butamirate was administered at 25 drops inside 4 times/day for 4,9 ± 0,8 days. In the comparison group – 21 children – antitussives were used according to the protocol for the treatment of acute bronchitis.Results. In 80,3 ± 5,4% of patients in the main (1 and 2) groups, by the fourth day of treatment with butamirate in relation to the comparison group, the state of health improved (0,5 ± 0,07 points, p = 0,032), the intensity of cough decreased (0,1 ± 0,01 points, p = 0,015), dry cough leveled out (0,3 ± 0,02 points, p = 0,023), the cough period decreased with exhausting cough (0,2 ± 0,01 points, p = 0,017). There were no statistically significant differences between the two main groups. In no case did butamirate cause respiratory depression, impairment of cognitive functions, sedation and drug dependence. In the comparison group, the patients’ state of health improved less intensely, the characteristics of dry cough persisted for a longer time.Conclusions. Butamirate is effective and safe in the treatment of dry cough in acute bronchitis in preschoolers. |
| first_indexed | 2024-04-09T16:31:41Z |
| format | Article |
| id | doaj.art-445c11194e00438b9169d374f9c918fe |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:31:41Z |
| publishDate | 2020-11-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-445c11194e00438b9169d374f9c918fe2023-04-23T06:57:03ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902020-11-01018586410.21518/2079-701X-2020-18-58-645362The potential of the use of antitude therapy in pediatric practiceE. L. Rashitova0A. M. Zakirova1T. B. Moroz2D. T. Shayapova3A. G. Kadriev4A. A. Kadriev5Federal State Budgetary Educational Institution of Higher Education “Kazan State Medical University” of the Ministry of Health of the Russian FederationFederal State Budgetary Educational Institution of Higher Education “Kazan State Medical University” of the Ministry of Health of the Russian FederationChildren’s Hospital, State Autonomous Healthcare Institution “Central City Clinical Hospital No. 18”Children’s Hospital, State Autonomous Healthcare Institution “Central City Clinical Hospital No. 18”Federal State Budgetary Educational Institution of Higher Education “Kazan State Medical University” of the Ministry of Health of the Russian FederationFederal State Budgetary Educational Institution of Higher Education “Kazan State Medical University” of the Ministry of Health of the Russian FederationIntroduction.Coughing affects quality of life and is the most common reason patients seek medical attention. In children, establishing the pathophysiological cause of the condition associated with cough is of particular importance for making an adequate diagnosis and prescribing the correct therapy.Target. To assess the efficacy and safety of butamirate use in the complex treatment of preschoolers with acute bronchitis.Materials and methods. The initiative study was carried out in accordance with the requirements of the Declaration of Helsinki and included 63 patients with a dry cough symptom at the age of 3–7 years with a diagnosis of acute bronchitis. The effectiveness of therapy was assessed using a point system. In the main (1) group – 21 children – used a non-narcotic antitussive drug of central action butamirate, 5 ml of syrup 3 times/day before meals for 4,7 ± 0,6 days. In the main (2) group – 21 children – butamirate was administered at 25 drops inside 4 times/day for 4,9 ± 0,8 days. In the comparison group – 21 children – antitussives were used according to the protocol for the treatment of acute bronchitis.Results. In 80,3 ± 5,4% of patients in the main (1 and 2) groups, by the fourth day of treatment with butamirate in relation to the comparison group, the state of health improved (0,5 ± 0,07 points, p = 0,032), the intensity of cough decreased (0,1 ± 0,01 points, p = 0,015), dry cough leveled out (0,3 ± 0,02 points, p = 0,023), the cough period decreased with exhausting cough (0,2 ± 0,01 points, p = 0,017). There were no statistically significant differences between the two main groups. In no case did butamirate cause respiratory depression, impairment of cognitive functions, sedation and drug dependence. In the comparison group, the patients’ state of health improved less intensely, the characteristics of dry cough persisted for a longer time.Conclusions. Butamirate is effective and safe in the treatment of dry cough in acute bronchitis in preschoolers.https://www.med-sovet.pro/jour/article/view/5895childrenbutamiratedry coughbronchitispreschool age |
| spellingShingle | E. L. Rashitova A. M. Zakirova T. B. Moroz D. T. Shayapova A. G. Kadriev A. A. Kadriev The potential of the use of antitude therapy in pediatric practice Медицинский совет children butamirate dry cough bronchitis preschool age |
| title | The potential of the use of antitude therapy in pediatric practice |
| title_full | The potential of the use of antitude therapy in pediatric practice |
| title_fullStr | The potential of the use of antitude therapy in pediatric practice |
| title_full_unstemmed | The potential of the use of antitude therapy in pediatric practice |
| title_short | The potential of the use of antitude therapy in pediatric practice |
| title_sort | potential of the use of antitude therapy in pediatric practice |
| topic | children butamirate dry cough bronchitis preschool age |
| url | https://www.med-sovet.pro/jour/article/view/5895 |
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