Recommendations for the Development of CFD Model to Assess the Thrombogenic Potential of Stents
Computational fluid dynamics (CFD) has enormous potential for the development of novel cardiovascular implants. In particular, the evaluation of the thrombogenic potential of implants is gaining importance. For this purpose, the numerical model must represent the essential properties of the real sys...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2022-09-01
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| Series: | Current Directions in Biomedical Engineering |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/cdbme-2022-1133 |
| _version_ | 1827998253597065216 |
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| author | Stiehm Michael Borowski Finja Oldenburg Jan Öner Alper Schmitz Klaus-Peter |
| author_facet | Stiehm Michael Borowski Finja Oldenburg Jan Öner Alper Schmitz Klaus-Peter |
| author_sort | Stiehm Michael |
| collection | DOAJ |
| description | Computational fluid dynamics (CFD) has enormous potential for the development of novel cardiovascular implants. In particular, the evaluation of the thrombogenic potential of implants is gaining importance. For this purpose, the numerical model must represent the essential properties of the real system, i.e., an implant in the human blood circulation, in a suitable form. Due to its complexity, the model building process is crucial for the successful application of the model. Currently, there is no structured guideline for the application of numerical flow simulation to which model developers can refer. Based on NASA and ASTM, we present key aspects of the model building process using CFD for stent flow as an example. |
| first_indexed | 2024-04-10T05:40:51Z |
| format | Article |
| id | doaj.art-4460d5a8d3554dbba77c5ad2772f35f1 |
| institution | Directory Open Access Journal |
| issn | 2364-5504 |
| language | English |
| last_indexed | 2024-04-10T05:40:51Z |
| publishDate | 2022-09-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Current Directions in Biomedical Engineering |
| spelling | doaj.art-4460d5a8d3554dbba77c5ad2772f35f12023-03-06T10:24:52ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042022-09-018252052310.1515/cdbme-2022-1133Recommendations for the Development of CFD Model to Assess the Thrombogenic Potential of StentsStiehm Michael0Borowski Finja1Oldenburg Jan2Öner Alper3Schmitz Klaus-Peter4Institute for ImplantTechnology and Biomaterials e.V., Friedrich-Barnewitz-Str. 4, 18119Rostock-Warnemunde, GermanyInstitute for ImplantTechnology and Biomaterials e.V.,Rostock-Warnemunde, GermanyInstitute for ImplantTechnology and Biomaterials e.V.,Rostock-Warnemunde, GermanyDepartment of Cardiology Rostock University Medical Center,Rostock, GermanyInstitute for ImplantTechnology and Biomaterials e.V.,Rostock-Warnemunde, GermanyComputational fluid dynamics (CFD) has enormous potential for the development of novel cardiovascular implants. In particular, the evaluation of the thrombogenic potential of implants is gaining importance. For this purpose, the numerical model must represent the essential properties of the real system, i.e., an implant in the human blood circulation, in a suitable form. Due to its complexity, the model building process is crucial for the successful application of the model. Currently, there is no structured guideline for the application of numerical flow simulation to which model developers can refer. Based on NASA and ASTM, we present key aspects of the model building process using CFD for stent flow as an example.https://doi.org/10.1515/cdbme-2022-1133validationverificationcomputational fluid dynamicsblood flow |
| spellingShingle | Stiehm Michael Borowski Finja Oldenburg Jan Öner Alper Schmitz Klaus-Peter Recommendations for the Development of CFD Model to Assess the Thrombogenic Potential of Stents Current Directions in Biomedical Engineering validation verification computational fluid dynamics blood flow |
| title | Recommendations for the Development of CFD Model to Assess the Thrombogenic Potential of Stents |
| title_full | Recommendations for the Development of CFD Model to Assess the Thrombogenic Potential of Stents |
| title_fullStr | Recommendations for the Development of CFD Model to Assess the Thrombogenic Potential of Stents |
| title_full_unstemmed | Recommendations for the Development of CFD Model to Assess the Thrombogenic Potential of Stents |
| title_short | Recommendations for the Development of CFD Model to Assess the Thrombogenic Potential of Stents |
| title_sort | recommendations for the development of cfd model to assess the thrombogenic potential of stents |
| topic | validation verification computational fluid dynamics blood flow |
| url | https://doi.org/10.1515/cdbme-2022-1133 |
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