Metabotropic glutamate receptors (mGluRs) in epileptogenesis: an update on abnormal mGluRs signaling and its therapeutic implications

Metabotropic glutamate receptors (mGluRs) in epileptogenesis: an update on abnormal mGluRs signaling and its therapeutic implications

Epilepsy is a neurological disorder characterized by high morbidity, high recurrence, and drug resistance. Enhanced signaling through the excitatory neurotransmitter glutamate is intricately associated with epilepsy. Metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors activated...

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Hlavní autoři: Leyi Huang, Wenjie Xiao, Yan Wang, Juan Li, Jiaoe Gong, Ewen Tu, Lili Long, Bo Xiao, Xiaoxin Yan, Lily Wan
Médium: Článek
Jazyk:English
Vydáno: Wolters Kluwer Medknow Publications 2024-01-01
Edice:Neural Regeneration Research
Témata:
antiepileptic drugs; epileptogenesis; metabotropic glutamate receptors (mglurs); signal pathways; therapeutic potentials
On-line přístup:http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=2;spage=360;epage=368;aulast=

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=2;spage=360;epage=368;aulast=

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