Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait
While human lifespan is only moderately heritable, “getting old” runs in families. Here, van den Berg et al. study mortality data from three-generation cohorts to define a threshold for longevity and find that individuals have an increasing survival advantage with each additional relative in the top...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-07925-0 |
| _version_ | 1818749149137338368 |
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| author | Niels van den Berg Mar Rodríguez-Girondo Ingrid K. van Dijk Rick J. Mourits Kees Mandemakers Angelique A. P. O. Janssens Marian Beekman Ken R. Smith P. Eline Slagboom |
| author_facet | Niels van den Berg Mar Rodríguez-Girondo Ingrid K. van Dijk Rick J. Mourits Kees Mandemakers Angelique A. P. O. Janssens Marian Beekman Ken R. Smith P. Eline Slagboom |
| author_sort | Niels van den Berg |
| collection | DOAJ |
| description | While human lifespan is only moderately heritable, “getting old” runs in families. Here, van den Berg et al. study mortality data from three-generation cohorts to define a threshold for longevity and find that individuals have an increasing survival advantage with each additional relative in the top 10% survivors of their birth cohort. |
| first_indexed | 2024-12-18T03:59:11Z |
| format | Article |
| id | doaj.art-44642dfb9cb94830b8332d5e5db86fc0 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-18T03:59:11Z |
| publishDate | 2019-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-44642dfb9cb94830b8332d5e5db86fc02022-12-21T21:21:43ZengNature PortfolioNature Communications2041-17232019-01-0110111210.1038/s41467-018-07925-0Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic traitNiels van den Berg0Mar Rodríguez-Girondo1Ingrid K. van Dijk2Rick J. Mourits3Kees Mandemakers4Angelique A. P. O. Janssens5Marian Beekman6Ken R. Smith7P. Eline Slagboom8Department of Biomedical Data Sciences, Section of Molecular Epidemiology, Leiden University Medical CenterDepartment of Biomedical Data Sciences, Section of Medical Statistics, Leiden University Medical CenterRadboud Group for Historical Demography and Family History, Radboud UniversityRadboud Group for Historical Demography and Family History, Radboud UniversityInternational Institute of Social HistoryRadboud Group for Historical Demography and Family History, Radboud UniversityDepartment of Biomedical Data Sciences, Section of Molecular Epidemiology, Leiden University Medical CenterDepartment of Family and Consumer Studies, Population Sciences, Huntsman Cancer Institute, University of UtahDepartment of Biomedical Data Sciences, Section of Molecular Epidemiology, Leiden University Medical CenterWhile human lifespan is only moderately heritable, “getting old” runs in families. Here, van den Berg et al. study mortality data from three-generation cohorts to define a threshold for longevity and find that individuals have an increasing survival advantage with each additional relative in the top 10% survivors of their birth cohort.https://doi.org/10.1038/s41467-018-07925-0 |
| spellingShingle | Niels van den Berg Mar Rodríguez-Girondo Ingrid K. van Dijk Rick J. Mourits Kees Mandemakers Angelique A. P. O. Janssens Marian Beekman Ken R. Smith P. Eline Slagboom Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait Nature Communications |
| title | Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait |
| title_full | Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait |
| title_fullStr | Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait |
| title_full_unstemmed | Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait |
| title_short | Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait |
| title_sort | longevity defined as top 10 survivors and beyond is transmitted as a quantitative genetic trait |
| url | https://doi.org/10.1038/s41467-018-07925-0 |
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