Phenolic content of Sicilian virgin olive oils and their effect on MG-63 human osteoblastic cell proliferation
The aim of this study was, first, to investigate the influence of olive variety and elevation of orchards on the phenolic compound content of Sicilian virgin olive oils (VOOs) and, second, to investigate the effects of VOO phenolic extracts on osteoblast cell growth using the human MG-63 osteosarcom...
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| Format: | Article |
| Language: | English |
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Consejo Superior de Investigaciones Científicas
2014-09-01
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| Series: | Grasas y Aceites |
| Subjects: | |
| Online Access: | http://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/1497 |
| _version_ | 1831545703824883712 |
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| author | O. García-Martínez G. Mazzaglia A. Sánchez-Ortiz F. M. Ocaña-Peinado A. Rivas |
| author_facet | O. García-Martínez G. Mazzaglia A. Sánchez-Ortiz F. M. Ocaña-Peinado A. Rivas |
| author_sort | O. García-Martínez |
| collection | DOAJ |
| description | The aim of this study was, first, to investigate the influence of olive variety and elevation of orchards on the phenolic compound content of Sicilian virgin olive oils (VOOs) and, second, to investigate the effects of VOO phenolic extracts on osteoblast cell growth using the human MG-63 osteosarcoma cell line. Olive oil phenolic content and its effect on human osteosarcoma cell proliferation varied according to the type of cultivar and the grove altitude. This variation was also observed within the same type of cultivar. This observation demonstrates that the cultivar and the grove location can significantly affect the chemical composition and bioactivity of virgin olive oil. Although this study supports the hypothesis that virgin olive oil phenolic fractions exert a beneficial effect on bone health, further studies assessing the in vivo accessibility of virgin olive oil phenolic compounds to osteoblast cells should be carried out. |
| first_indexed | 2024-12-17T01:32:12Z |
| format | Article |
| id | doaj.art-44664914d56840a087ad00c936b51e62 |
| institution | Directory Open Access Journal |
| issn | 0017-3495 1988-4214 |
| language | English |
| last_indexed | 2024-12-17T01:32:12Z |
| publishDate | 2014-09-01 |
| publisher | Consejo Superior de Investigaciones Científicas |
| record_format | Article |
| series | Grasas y Aceites |
| spelling | doaj.art-44664914d56840a087ad00c936b51e622022-12-21T22:08:32ZengConsejo Superior de Investigaciones CientíficasGrasas y Aceites0017-34951988-42142014-09-01653e032e03210.3989/gya.01111411465Phenolic content of Sicilian virgin olive oils and their effect on MG-63 human osteoblastic cell proliferationO. García-Martínez0G. Mazzaglia1A. Sánchez-Ortiz2F. M. Ocaña-Peinado3A. Rivas4Faculty of Health Sciences, University of GranadaFaculty of Health Sciences, University of Granada - Private practiceAgricultural Research Training Centre, Ministry of Agriculture and FisheriesDepartment of Statistics and Operations Research, Faculty of Pharmacy, University of GranadaFaculty of Pharmacy, University of GranadaThe aim of this study was, first, to investigate the influence of olive variety and elevation of orchards on the phenolic compound content of Sicilian virgin olive oils (VOOs) and, second, to investigate the effects of VOO phenolic extracts on osteoblast cell growth using the human MG-63 osteosarcoma cell line. Olive oil phenolic content and its effect on human osteosarcoma cell proliferation varied according to the type of cultivar and the grove altitude. This variation was also observed within the same type of cultivar. This observation demonstrates that the cultivar and the grove location can significantly affect the chemical composition and bioactivity of virgin olive oil. Although this study supports the hypothesis that virgin olive oil phenolic fractions exert a beneficial effect on bone health, further studies assessing the in vivo accessibility of virgin olive oil phenolic compounds to osteoblast cells should be carried out.http://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/1497osteoblastic cellsphenolic compoundsproliferationsicilyvirgin olive oil |
| spellingShingle | O. García-Martínez G. Mazzaglia A. Sánchez-Ortiz F. M. Ocaña-Peinado A. Rivas Phenolic content of Sicilian virgin olive oils and their effect on MG-63 human osteoblastic cell proliferation Grasas y Aceites osteoblastic cells phenolic compounds proliferation sicily virgin olive oil |
| title | Phenolic content of Sicilian virgin olive oils and their effect on MG-63 human osteoblastic cell proliferation |
| title_full | Phenolic content of Sicilian virgin olive oils and their effect on MG-63 human osteoblastic cell proliferation |
| title_fullStr | Phenolic content of Sicilian virgin olive oils and their effect on MG-63 human osteoblastic cell proliferation |
| title_full_unstemmed | Phenolic content of Sicilian virgin olive oils and their effect on MG-63 human osteoblastic cell proliferation |
| title_short | Phenolic content of Sicilian virgin olive oils and their effect on MG-63 human osteoblastic cell proliferation |
| title_sort | phenolic content of sicilian virgin olive oils and their effect on mg 63 human osteoblastic cell proliferation |
| topic | osteoblastic cells phenolic compounds proliferation sicily virgin olive oil |
| url | http://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/1497 |
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