Is Wheat Glutenin Extract Intrinsically Allergenic? Evaluation Using a Novel Adjuvant-Free Mouse Model of Systemic Anaphylaxis

Is Wheat Glutenin Extract Intrinsically Allergenic? Evaluation Using a Novel Adjuvant-Free Mouse Model of Systemic Anaphylaxis

Wheat is a prominent allergenic food that can trigger life-threatening anaphylaxis. Presently, it remains unclear whether wheat glutenin (WG) extract possesses inherent sensitization potential independently, without the use of adjuvants, and whether it can sensitize mice to the extent of inducing li...

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Bibliographic Details
Main Authors: Rick Jorgensen, Haoran Gao, Tamil Selvan Arul Arasan, Chris Van Antwerp, Vaisheswini Sundar, Perry K. W. Ng, Venu Gangur
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
glutenin allergy
skin sensitization
systemic anaphylaxis
IgE
mouse model
Online Access:https://www.mdpi.com/1422-0067/24/24/17247

Internet

https://www.mdpi.com/1422-0067/24/24/17247

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