Vascular calcification in patients with chronic kidney disease on dialysis in the Kingdom of Saudi Arabia: A cross-sectional study
The study aimed to provide a unique nationwide data and a valuable update on the current situation of vascular calcification (VC) among chronic kidney disease (CKD) patients in the Kingdom of Saudi Arabia. The study included all patients diagnosed with CKD over a period of one year and six months fr...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | Saudi Journal of Kidney Diseases and Transplantation |
| Online Access: | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2019;volume=30;issue=3;spage=571;epage=580;aulast=AlGhonaim |
| _version_ | 1818623759586689024 |
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| author | Mohammed Abdulrahman AlGhonaim Adel A Fathalla |
| author_facet | Mohammed Abdulrahman AlGhonaim Adel A Fathalla |
| author_sort | Mohammed Abdulrahman AlGhonaim |
| collection | DOAJ |
| description | The study aimed to provide a unique nationwide data and a valuable update on the current situation of vascular calcification (VC) among chronic kidney disease (CKD) patients in the Kingdom of Saudi Arabia. The study included all patients diagnosed with CKD over a period of one year and six months from September 2015 to February 2017 and underwent dialysis. All analyses were done using IBM-SPSS. Of the 842 enrolled patients, 836 (99.3%) constituted the descriptive population. The mean age of patients was 51.8 ± 15.4 years. A total of 759 (90.8%) patients had cardiovascular risk factors. The prevalence of VC in patients with CKD is 40.8%. In the multivariate analysis, prognostic factors for VC were physical inactivity with odd ratio 2.87 [95% confidence interval (CI): (1.89–4.63), P < 0.01], history of ischemic heart disease 2.34 [95% CI: (1.30–4.22), P < 0.01], dyslipidemia 1.56 [95% CI: (1.01–2.40), P = 0.04], and older age 1.06 [95% CI: (1.05–1.07), P <0.01]. At inclusion, the mean ± standard deviation for high-density lipoprotein cholesterol, low cholesterol, total cholesterol, and triglycerides was 41 ± 30, 79.7 ± 29.9, 144.2 ± 38.5, and 143.4 ± 95.3 mg/dL, respectively. This study reports useful information about the prevalence of VCs in CKD stage 5D in a Middle Eastern country as the Kingdom of Saudi Arabia. Furthermore, it offers information on the predictors or associated factors of a VC in CKD patients. |
| first_indexed | 2024-12-16T18:46:10Z |
| format | Article |
| id | doaj.art-446b81c3c16a4cd09e0bb21173e47db8 |
| institution | Directory Open Access Journal |
| issn | 1319-2442 |
| language | English |
| last_indexed | 2024-12-16T18:46:10Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Kidney Diseases and Transplantation |
| spelling | doaj.art-446b81c3c16a4cd09e0bb21173e47db82022-12-21T22:20:50ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422019-01-0130357158010.4103/1319-2442.261329Vascular calcification in patients with chronic kidney disease on dialysis in the Kingdom of Saudi Arabia: A cross-sectional studyMohammed Abdulrahman AlGhonaimAdel A FathallaThe study aimed to provide a unique nationwide data and a valuable update on the current situation of vascular calcification (VC) among chronic kidney disease (CKD) patients in the Kingdom of Saudi Arabia. The study included all patients diagnosed with CKD over a period of one year and six months from September 2015 to February 2017 and underwent dialysis. All analyses were done using IBM-SPSS. Of the 842 enrolled patients, 836 (99.3%) constituted the descriptive population. The mean age of patients was 51.8 ± 15.4 years. A total of 759 (90.8%) patients had cardiovascular risk factors. The prevalence of VC in patients with CKD is 40.8%. In the multivariate analysis, prognostic factors for VC were physical inactivity with odd ratio 2.87 [95% confidence interval (CI): (1.89–4.63), P < 0.01], history of ischemic heart disease 2.34 [95% CI: (1.30–4.22), P < 0.01], dyslipidemia 1.56 [95% CI: (1.01–2.40), P = 0.04], and older age 1.06 [95% CI: (1.05–1.07), P <0.01]. At inclusion, the mean ± standard deviation for high-density lipoprotein cholesterol, low cholesterol, total cholesterol, and triglycerides was 41 ± 30, 79.7 ± 29.9, 144.2 ± 38.5, and 143.4 ± 95.3 mg/dL, respectively. This study reports useful information about the prevalence of VCs in CKD stage 5D in a Middle Eastern country as the Kingdom of Saudi Arabia. Furthermore, it offers information on the predictors or associated factors of a VC in CKD patients.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2019;volume=30;issue=3;spage=571;epage=580;aulast=AlGhonaim |
| spellingShingle | Mohammed Abdulrahman AlGhonaim Adel A Fathalla Vascular calcification in patients with chronic kidney disease on dialysis in the Kingdom of Saudi Arabia: A cross-sectional study Saudi Journal of Kidney Diseases and Transplantation |
| title | Vascular calcification in patients with chronic kidney disease on dialysis in the Kingdom of Saudi Arabia: A cross-sectional study |
| title_full | Vascular calcification in patients with chronic kidney disease on dialysis in the Kingdom of Saudi Arabia: A cross-sectional study |
| title_fullStr | Vascular calcification in patients with chronic kidney disease on dialysis in the Kingdom of Saudi Arabia: A cross-sectional study |
| title_full_unstemmed | Vascular calcification in patients with chronic kidney disease on dialysis in the Kingdom of Saudi Arabia: A cross-sectional study |
| title_short | Vascular calcification in patients with chronic kidney disease on dialysis in the Kingdom of Saudi Arabia: A cross-sectional study |
| title_sort | vascular calcification in patients with chronic kidney disease on dialysis in the kingdom of saudi arabia a cross sectional study |
| url | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2019;volume=30;issue=3;spage=571;epage=580;aulast=AlGhonaim |
| work_keys_str_mv | AT mohammedabdulrahmanalghonaim vascularcalcificationinpatientswithchronickidneydiseaseondialysisinthekingdomofsaudiarabiaacrosssectionalstudy AT adelafathalla vascularcalcificationinpatientswithchronickidneydiseaseondialysisinthekingdomofsaudiarabiaacrosssectionalstudy |