Chemopreventive Effects of <i>Onosma mutabilis</i> against Azoxymethane-Induced Colon Cancer in Rats via Amendment of Bax/Bcl-2 and NF-κB Signaling Pathways

Chemopreventive Effects of <i>Onosma mutabilis</i> against Azoxymethane-Induced Colon Cancer in Rats via Amendment of Bax/Bcl-2 and NF-κB Signaling Pathways

<i>Onosma</i> species (Boraginaceae) are well known as medicinal plants due to their wide range of pharmaceutical potential. The present study aims to investigate the anticancer (in vitro) and chemo-protective (in vivo) efficacies of <i>Onosma mutabilis</i> extract (OME) in t...

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Bibliographic Details
Main Authors: Ahmed Aj. Jabbar, Ibrahim Abdel Aziz Ibrahim, Fuad O. Abdullah, Kareem Fattah Aziz, Abdullah R. Alzahrani, Mahmood Ameen Abdulla
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Current Issues in Molecular Biology
Subjects:
colon cancer
Boraginaceae
chemoprevention
oxidative stress
histopathology
Online Access:https://www.mdpi.com/1467-3045/45/2/57

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