Current Knowledge on Exosome Biogenesis, Cargo-Sorting Mechanism and Therapeutic Implications

Current Knowledge on Exosome Biogenesis, Cargo-Sorting Mechanism and Therapeutic Implications

Extracellular vesicles (EVs) are nanoscale membrane vesicles released by donor cells that can be taken up by recipient cells. The study of EVs has the potential to identify unknown cellular and molecular mechanisms in intercellular communication and disease. Exosomes, with an average diameter of ≈10...

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Bibliographic Details
Main Authors: Shenmin Xie, Qin Zhang, Li Jiang
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Membranes
Subjects:
exosomes
biogenesis
cargo sorting
ESCRT
microRNA
bioengineering
Online Access:https://www.mdpi.com/2077-0375/12/5/498

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