T-cell receptor and K-deleting recombination excision circles in newborn screening of T- and B-cell defects: review of the literature and future challenges

T-cell receptor and K-deleting recombination excision circles in newborn screening of T- and B-cell defects: review of the literature and future challenges

Since its introduction as a public health programme in the United States in the early 1960s, newborn blood screening (NBS) has evolved from the detection of phenylalanine levels on filter paper to the application of DNA-based technologies to identify T-cell lymphopenia in infants with severe combine...

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Bibliographic Details
Main Authors: Marco Chiarini, Cinzia Zanotti, Federico Serana, Alessandra Sottini, Diego Bertoli, Luigi Caimi, Luisa Imberti
Format: Article
Language:English
Published: SAGE Publishing 2013-05-01
Series:Journal of Public Health Research
Subjects:
primary immunodeficiency, severe combined immunodeficiency, T-cell receptor excision circles, K-deleting recombination excision circles, newborn screening
Online Access:http://www.jphres.org/index.php/jphres/article/view/114

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